Results 141 to 150 of about 1,138,097 (292)

Renal transplantation in older recipients - results of the DZIF transplant cohort. [PDF]

BMC Geriatr
Sommerer C, Schröter I, Schindler D, Schork A, Renders L, Kemmner S, Willerding JM, Tönshoff B, Zeier M, Giese T, Transplant Cohort of the German Center for Infection Research (DZIF Transplant Cohort) Consortium.   +10 more
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Incidence and Risk Factors of Obesity and Overweight in Kidney Transplant Recipients and Their Effect on Graft Outcome

Journal of Transplantation
Muhammad Abdul Mabood Khalil, Nihal Mohammed Sadagah, Hinda Hassan Khideer Mahmood, Abdulrahman Ibn Almuataz Wasfi Ezzi, Sultan Abdullah M. Alghamdi, Faisal Saud H. Alsulami, Ahmed Abdelahad Basha, Mohamed Abdelmonem Said Ahmed, Islam Nabil Sharabas, Hitham Abdallah Ahmed Abdallah Ragab, Aileen Jean Dela Cruz, Ghaleb Anas Aboalsamh, Salem H. Al-Qurashi   +12 more
doaj   +1 more source

Editorial: Community series in renal fibrosis and renal transplantation, volume II. [PDF]

Front Immunol
Yang C.
europepmc   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

Advanced Science, EarlyView.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li, Junting Guan, Yifan Song, Hongxia Yang, Guangtao Li, Xiaodong Zhao, Jiaxin Liu, Bin Liu, Yang Tan, Honglan Zhou, Yang‐He Zhang, Yishu Wang   +11 more
wiley   +1 more source

Renal transplantation and variations in blood supply: a narrative review. [PDF]

Front Transplant
Thrailkill S, Alashkham A, Elajnaf M, Almabrouk T.   +3 more
europepmc   +1 more source

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

Advanced Science, EarlyView.
Magnetoreceptor (MagR) regulates iron homeostasis and mitochondrial function in hepatocellular carcinoma (HCC) cells. Specifically, MagR deficiency suppresses tumor cell proliferation, migration, and invasion and enhances sorafenib‐induced ferroptosis through iron accumulation.
Tao Wang, Chenghua Song, Xin He, Mengzhou Wang, Wuming Liu, Xiaolin Wang, Yuanyuan Zhang, Jia Zhang, Lin Zhang, Dan Li, Yu Zhang, Zheng Wu, Yi Lyu, Rongqian Wu   +13 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Editorial: Renal fibrosis and renal transplantation. [PDF]

Front Immunol
Yang C.
europepmc   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source