Results 71 to 80 of about 19,914 (203)

Renal Tubular Acidosis and Hypokalemic Paralysis as a First Presentation of Primary Sjögren’s Syndrome

Case Reports in Nephrology, 2018
Sjögren’s syndrome is an autoimmune disease with multisystem involvement and varying clinical presentation. We report the clinical course and outcome of a case who presented with repeated episodes of hypokalemia mimicking hypokalemic periodic paralysis ...
Arun Sedhain, Kiran Acharya, Alok Sharma, Amir Khan, Shital Adhikari   +4 more
doaj   +1 more source

Acute-onset paralysis in a patient of rheumatoid arthritis

Annals of Saudi Medicine, 2015
Renal tubular acidosis (RTA) is a disorder of renal acidification characterized by inability to acidify urine to pH
Ankur Nandan Varshney, Pratibha Prasad, Nilesh Kumar, Nand Kumar Singh   +3 more
doaj   +1 more source

Gene‐Guided Therapy in Type 2 Diabetes Mellitus: An Integrative Review of the Pharmacogenetics of Metformin and Sodium‐Glucose Cotransporter‐2 Inhibitors

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Genetic variation influences the pharmacological response to metformin and SGLT2 inhibitors in patients with type 2 diabetes mellitus. Pharmacogenetic biomarkers affecting drug transport, metabolism and target activity contribute to inter‐individual differences in treatment efficacy and adverse effects, supporting the implementation of personalized ...
Imran Hossain, Mahnoor Haidar, Mahfuj Ahmed Ratul, Jannatul Ferdous Sumona, Sraboni Shabnaz, Abul Fojal Nokib, Fatema‐Tuz‐Zohora   +6 more
wiley   +1 more source

Distal renal tubular acidosis secondary to vesico-ureteric reflux: A case report with review of literature

Saudi Journal of Kidney Diseases and Transplantation, 2018
Vesicoureteric reflux (VUR) is the most common congenital anomaly of the urinary tract that occurs in 30%–50% of children presenting with recurrent urinary tract infections. Long-standing untreated VUR results in renal scarring and hydronephrotic changes
Anjali Bharani, Tanmay Bharani, Rajesh Bharani   +2 more
doaj   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Parathyroid carcinoma presenting with type 1 renal tubular acidosis

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2018
Primary hyperparathyroidism usually caused by parathyroid adenoma, parathyroid hyperplasia or rarely parathyroid carcinoma (PTC). PTC accounts for 0.4% to 5.2% of all reported cases of hyperparathyroidism, which is approximately 0.2% to 0.5% of malignant
S. A. S. Priyankara, K. Arulmoly, V. P. Jayasinghe, H. R. Thambawita, S. Ahilan, S. I. Majitha   +5 more
doaj   +1 more source

Tailored Amino Acid Treatment for Pediatric Patients With Mitochondrial Aminoacyl‐tRNA Synthetase Deficiencies

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) facilitate the loading of transfer RNAs with their cognate amino acids in the cytosol (ARS1), mitochondria (ARS2), or both (dual ARS). ARS deficiencies are clinically heterogeneous and can cause severe, occasionally fatal disease.
I. J. J. Muffels, G. Kok, Z. Tang, L. S. Medeiros, F. O. Poswar, W. P. Vermeij, R. Rodenburg, K. Smit, S. K. Sukumaran, S. B. Wortmann, L. Averdunk, J. Munch, J. Pak‐lam Ho, A. M. K. Kwok, E. E. S. Nieuwenhuis, P. M. van Hasselt, I. V. D. Schwartz, C. M. A. Lubout, A. M. Bosch, K. Koop, E. M. M. Hoytema van Konijnenburg, S. A. Fuchs   +21 more
wiley   +1 more source

Gastroschisis‐Like Defect in a Crossbred Bovine Calf: Anatomical, Clinical and Surgical Perspectives

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A gastroschisis‐like defect was observed in a one‐day‐old, crossbred bovine calf with evisceration of the pyloric abomasum and small intestine, likely resulting from prenatal rupture of an omphalocele. The calf presented with lethargy, hypothermia and metabolic derangements, along with elevated renal biomarkers.
Mohammad Raguib Munif, Tanjin Tamanna Mumu   +1 more
wiley   +1 more source

Nefrotoxicidad tubular proximal inducida por sobredosis de tenofovir: reporte de un caso de síndrome de Fanconi incompleto

Revista Médica Herediana
Mujer de 21 años admitida por intento autolítico tras ingesta de 28 tabletas de tenofovir/lamivudina/dolutegravir, administradas en el contexto de una profilaxis posexposición al virus de la inmunodeficiencia humana (VIH) luego de una agresión sexual ...
Esteban Ochoa-Robles, Glenda Jiménez-Alulima, Lenin Saltos-Iñiguez, Carlos Ortega-Espinoza, Maribel Carlosama-Mora   +4 more
doaj   +1 more source

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva, Luiz Gustavo dos Reis de Freitas, Akira Otake Hamoy, Clarissa Araujo da Paz, Luan Oliveira Ferreira, Esther Padilha da Silveira, Maria Klara Otake Hamoy, Nilton Akio Muto, Dielly Catrina Favacho Lopes, Moisés Hamoy   +9 more
wiley   +1 more source