Results 41 to 50 of about 721,252 (305)

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1. [PDF]

, 2018
Polybromo-1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl-lysine residues.
Alicea-Velázquez, Nilda L., Cai, Weijia, Cho, Eun-Ah, Cosgrove, Michael S., Greer, Celeste B., Langbein, Lauren, Liao, Lili, Niu, Xiaohua, Yan, Qin, Yang, Haifeng, Zhang, Meiling   +10 more
core   +2 more sources

Experience with Modified Makuuchi Incision in the Surgical Treatment of Huge Renal Tumor: A Single Institution's Experience

Journal of Medical Sciences
Background: Surgical removal of huge renal and retroperitoneal tumors, such as adrenal cortical carcinoma or renal cell carcinoma with inferior vena cava (IVC) invasion, remains a challenge for urologists. Aim: Herein, we describe our experience with the
Wei-Chen Yen, Meng-Hung Shih, Hui-Kung Ting, Yu-Cing Juho, Tai-Lung Cha, Chien-Chang Kao   +5 more
doaj   +1 more source

Nephrectomy and Tumor Thrombectomy with Concurrent Coronary Artery Bypass Graft for an HMB-45-Negative Giant Classical Renal Angiomyolipoma with Venous Extension

Journal of Urological Surgery, 2021
A 72-year-old woman was found to have a giant right renal mass (11.5 cm) suggestive of an angiomyolipoma (AML) on computed tomography imaging with atypical heterogeneity and grade III tumor thrombus extension into the inferior vena cava (IVC ...
Kathleen Lockhart, Nathan Shugg, Taranpreet Singh, Albert Tiu   +3 more
doaj   +1 more source

Patients With Kidney Cancer [PDF]

, 2012
To develop a preoperative prognostic model in order to predict recurrence-free survival in patients with nonmetastatic kidney cancer.A multi-institutional data base of 1889 patients who underwent surgical resection between 1987 and 2007 for kidney cancer
B. Soyupak, C. Gogus, E. Karabulut, H. Ozen, L. Turkeri, null null, O. Yaycioglu, S. Eskicorapci, S. Yazici, T. Divrik   +9 more
core   +2 more sources

Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients [PDF]

, 2020
BACKGROUND: RNA sequencing data is providing abundant information about the levels of dysregulation of genes in various tumors. These data, as well as data based on older microarray technologies have enabled the identification of many genes which are ...
Busch, Jonas, Hinze, Christian, Jung, Klaus, Jung, Monika, Rabien, Anja, Schmidt-Ott, Kai M., Simonovic, Sinisa   +6 more
core   +2 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery

Frontiers in Oncology, 2022
BackgroundWhen we treat renal cell carcinoma by laparoscopic nephron-sparing surgery (NSS), it is essential to use an evaluation system to predict clinical outcomes. Hitherto, there are more than a dozen nephrometry score systems.
Shudong Zhang, Zijian Qin, Hai Bi, Liyuan Tao, Fan Zhang, Hongxian Zhang, Wei Wang, Jitao Wu, Yi Huang, Lulin Ma   +9 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Congenital Mesoblastic Nephroma: Case Report

Revista de la Facultad de Medicina Humana, 2022
Congenital mesoblastic nephroma (CMN) is the most frequent renal tumor in newborns and infants. under 3 months. The clinical case of a patient younger than 3 months, with prenatal diagnosis, referred in a timely manner for evaluation and management by ...
Carolina F. Paz Soldán Mesta, José L. Apaza León, Mariela Tello Pezo, Roxana M. Lipa Chancolla   +3 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source