Results 31 to 40 of about 10,319 (171)

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In young patients with hypertension or stroke, the presence of bilateral parvus et tardus waveforms in the renal arteries should prompt reverse tracing to rule out aortic coarctation. This simple ultrasound clue enables early, non‐invasive screening and prevents missed diagnoses.
Yan‐li Chen, Jin‐hua Wang
wiley   +1 more source

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

The FEBS Journal, Volume 293, Issue 11, Page 3399-3414, June 2026.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source

Central Inhibition of Tumor Necrosis Factor Alpha Reduces Hypertension by Attenuating Oxidative Stress in the Rostral Ventrolateral Medulla in Renovascular Hypertensive Rats

Frontiers in Physiology, 2019
Inflammation in the central nervous system is being considered a key player linked to neurogenic hypertension. Using combined in vivo and in vitro approaches, we investigated the effects of central inhibition of TNF-α on blood pressure, sympathetic tone,
Alynne Carvalho-Galvão, Drielle D. Guimarães, Drielle D. Guimarães, José L. De Brito Alves, Valdir A. Braga, Valdir A. Braga   +5 more
doaj   +1 more source

Renal artery stenosis: the challenging in diagnosis and therapy

Український Журнал Нефрології та Діалізу, 2020
Hypertension is still the most prevalent non-communicable diseases in Indonesia. Renovascular hypertension is one type of secondary hypertension. It is commonly caused by the presence of renal artery stenosis (RAS).
Ivana P. Dewi, Kristin P. Dewi, N. Mardiana   +2 more
doaj   +1 more source

Statin Therapy Protects White Matter in Cerebral Small Vessel Disease Independent of Lipid‐Lowering: Biomarker and Neuroimaging Evidence

Brain and Behavior, Volume 16, Issue 5, May 2026.
This study, through an analysis of neuroimaging markers, biomarkers of white matter damage, and the volume of the hippocampal fimbria (a white matter structure) in patients with cerebral small vessel disease (CSVD), revealed that the protective effect of statin therapy against white matter damage in CSVD patients is independent of its lipid‐lowering ...
Rui Wang, Juluo Chen, Peiqi Ma, Lu Liu, Youmeng Wang, Qiqiang Tang   +5 more
wiley   +1 more source

Takayasu’s Arteritis Presenting as Heart Failure in a 19-Year-Old Female

JACC: Case Reports, 2019
This report presents the case of this atypical presentation of a rare disease in a 19-year-old female with cardiomyopathy and hypertension. Investigation revealed renovascular stenosis, infarcts, and active vasculitis pathognomonic for Takayasu arteritis
Andrew R. Benck, MD, Shivani Patel, MD, Emily Zern, MD, Kevin S. Shah, MD, Lillian R. Benck, MD, David Chang, MD, Chelsey J.F. Smith, MD, Michele A. Hamilton, MD   +7 more
doaj   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay, Alessia Brossa, Benedetta Bussolati   +2 more
wiley   +1 more source

Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension

Heliyon
Endothelial dysfunction and inflammation are clinically significant risk factors for cardiovascular diseases in hypertension. Although immune cells play a role in hypertension, the impact of plasmacytoid dendritic cells in established renovascular ...
Balaji Srinivas, Kiran Alluri, Nour-Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +4 more
doaj   +1 more source

Spontaneous Renal Artery Dissection in a Normotensive Young Male

The Scientific World Journal, 2004
We report a case of spontaneous superior pole renal artery dissection in a healthy forty-one year old man. Spontaneous renal artery dissection is a rare event occurring in patients with hypertension or renovascular disease such as fibromuscular dysplasia.
John A. Taylor, Eric C. Martin, Ihor S. Sawczuk   +2 more
doaj   +1 more source