Results 41 to 50 of about 23,020 (220)

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

The FEBS Journal, EarlyView.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source

Takayasu’s Arteritis Presenting as Heart Failure in a 19-Year-Old Female

JACC: Case Reports, 2019
This report presents the case of this atypical presentation of a rare disease in a 19-year-old female with cardiomyopathy and hypertension. Investigation revealed renovascular stenosis, infarcts, and active vasculitis pathognomonic for Takayasu arteritis
Andrew R. Benck, MD, Shivani Patel, MD, Emily Zern, MD, Kevin S. Shah, MD, Lillian R. Benck, MD, David Chang, MD, Chelsey J.F. Smith, MD, Michele A. Hamilton, MD   +7 more
doaj   +1 more source

Renovascular hypertension: a case with atypical neurological signs [PDF]

, 2015
Secondary hypertension is the most frequent form of hypertension in children. Renovascular disease accounts for 5-10% of all childhood hypertension and should be suspected in the presence of severe hypertension found difficult to manage with medical ...
Dionísio, T, Gomes, C, Jerónimo, M, Neves, JF   +3 more
core   +1 more source

Statin Therapy Protects White Matter in Cerebral Small Vessel Disease Independent of Lipid‐Lowering: Biomarker and Neuroimaging Evidence

Brain and Behavior, Volume 16, Issue 5, May 2026.
This study, through an analysis of neuroimaging markers, biomarkers of white matter damage, and the volume of the hippocampal fimbria (a white matter structure) in patients with cerebral small vessel disease (CSVD), revealed that the protective effect of statin therapy against white matter damage in CSVD patients is independent of its lipid‐lowering ...
Rui Wang, Juluo Chen, Peiqi Ma, Lu Liu, Youmeng Wang, Qiqiang Tang   +5 more
wiley   +1 more source

Hipertensión renovascular: actualización

Nefrología Latinoamericana, 2020
La hipertensión renovascular (HTRV) es una causa frecuente y potencialmente corregible de hipertensión arterial (HTA) secundaria. Su incidencia varía en función del contexto clínico. Se encuentra estenosis de la arteria renal (EAR) en 1% de los pacientes
Ricardo Silvariño, José Boggia, Sofía San Román, Cecilia Baccino, Alejandro Crisci, Marcelo Langleib, Óscar Noboa   +6 more
doaj   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay, Alessia Brossa, Benedetta Bussolati   +2 more
wiley   +1 more source

Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension

Heliyon
Endothelial dysfunction and inflammation are clinically significant risk factors for cardiovascular diseases in hypertension. Although immune cells play a role in hypertension, the impact of plasmacytoid dendritic cells in established renovascular ...
Balaji Srinivas, Kiran Alluri, Nour-Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +4 more
doaj   +1 more source

Spontaneous Renal Artery Dissection in a Normotensive Young Male

The Scientific World Journal, 2004
We report a case of spontaneous superior pole renal artery dissection in a healthy forty-one year old man. Spontaneous renal artery dissection is a rare event occurring in patients with hypertension or renovascular disease such as fibromuscular dysplasia.
John A. Taylor, Eric C. Martin, Ihor S. Sawczuk   +2 more
doaj   +1 more source

Renal artery fibromuscular dysplasia: diagnostic challenges in a child presenting with hyponatremic hypertensive syndrome (HHS)

Journal of Pediatric and Neonatal Individualized Medicine
A 2-year-9-month-old boy presented with renovascular hypertension caused by middle-segment stenosis of the right renal artery, and a severe hypertensive crisis, accompanied by hyponatremia, hypokalemia, and transient proteinuria. Fibromuscular dysplasia (
Asrar Abu Bakar, Sharifah Aishah Syed Ahmad Alsagoff, Muhamad Azamin Anuar, Ganeshwara Durai Raja Lingam   +3 more
doaj   +1 more source

Open Partial Nephrectomy for Pediatric Renovascular Hypertension

The Scientific World Journal, 2009
Pediatric renovascular hypertension is typically managed with revascularization, angioplasty, or radical nephrectomy. We describe the case of a 13-year-old boy with medically refractory renovascular hypertension who presented to our institution after a ...
Matt S. Ashley, Gregory Moneta, Siamak Daneshmand   +2 more
doaj   +1 more source