Results 31 to 40 of about 23,300 (238)

No benefit of HIF prolyl hydroxylase inhibition for hypertensive renal damage in renovascular hypertensive rats

Frontiers in Physiology, 2023
Introduction: We previously reported that malignant hypertension is associated with impaired capillary density of target organs. Here, we tested the hypothesis that stabilization of hypoxia-inducible factor (HIF) in a modified “preconditioning” approach ...
Andrea Hartner, Thomas Dambietz, Nada Cordasic, Carsten Willam, Nicolai Burzlaff, Martin Brötsch, Christoph Daniel, Mario Schiffer, Kerstin Amann, Roland Veelken, Gunnar Schley, Karl F. Hilgers   +11 more
doaj   +1 more source

Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious
Adrian Santelli, In O. Sun, Alfonso Eirin, Abdelrhman M. Abumoawad, John R. Woollard, Amir Lerman, Stephen C. Textor, Amrutesh S. Puranik, Lilach O. Lerman   +8 more
doaj   +1 more source

Calcium Channel Blockers Are Associated With Improved Survival and Lower Cardiovascular Mortality in Patients With Renovascular Disease [PDF]

, 2019
Background and objective: Results of interventional trials in renovascular hypertension have been disappointing, and medical therapy is the current recommended gold standard.
Ambarasan, Thineshkrishna, Barker, Emma, Bell, Samira, Desmukh, Harshal, George, Jacob, Levin, Daniel, Witham, Miles D.   +6 more
core   +2 more sources

Vesicoureteral Reflux, a Scarred kidney, and Minimal Proteinuria: An Unusual Cause of Adult Secondary Hypertension

Case Reports in Medicine, 2011
Hypertension affects about 65 million individuals in the United States. In adult patients, primary aldosteronism and renovascular causes are described as most prevalent.
Shaifali Sandal, Apurv Khanna
doaj   +1 more source

Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin F2α impairs endothelial function in renovascular hypertensive rats [PDF]

, 2012
Aims: The role of endothelium-derived contracting factors (EDCFs) in regulating renovascular function is yet to be elucidated in renovascular hypertension (RH).
Au, CL, Chen, ZY, Cooke, JP, Huang, Y, Lau, CW, Lee, HK, Leung, FP, Ng, CF, Tian, XY, Vanhoutte, PM, Wang, YX, Wong, WT, Yao, X, Zhang, Y   +13 more
core   +1 more source

Renovascular hypertension

Kidney International, 1985
Renovascular hypertension is the most common cause of secondary hypertension. Interest in identifying patients with renal artery stenosis has been stimulated recently by advances in three areas. First, is the realization that not only can renal artery stenosis cause renovascular hypertension, but it can also lead to progressive renal failure (ischemic ...
openaire   +5 more sources

α-Lipoic Acid Reduces Hypertension and Increases Baroreflex Sensitivity in Renovascular Hypertensive Rats

Molecules, 2012
Renovascular hypertension has robust effects on control of blood pressure, including an impairment in baroreflex mechanisms, which involves oxidative stress.
Valdir A. Braga, Leônidas G. Mendes-Junior, Drielle D. Guimarães, Thyago M. Queiroz   +3 more
doaj   +1 more source

Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]

, 2011
<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H., Biondi, G., Colombo, A., Di Lauro, M.V., Gordon, P., Grassia, G., Guglielmotti, A., Ialenti, A., Kennedy, S., Maddaluno, M., Maffia, P.   +10 more
core   +1 more source

Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits

Experimental Physiology, EarlyView.
Abstract figure T‐type VGCCs contribute to the contraction of the rabbit aorta and modulate both contraction and vasodilation in the rabbit renal artery. α1, alpha 1 adrenergic receptor; ATR, angiotensin II receptor; Ang II, angiotensin II; CaM, calmodulin; Cav3, T‐type voltage‐gated Ca2⁺ channels; cGMP, cyclic guanidine monophosphate; EC, endothelial ...
Andrea Suarez, Sol Guerra‐Ojeda, Manuel Zarzoso, Marta Serna‐García, Jose M. Vila, Eva Serna, Maria D. Mauricio   +6 more
wiley   +1 more source

Renal artery fibromuscular dysplasia: diagnostic challenges in a child presenting with hyponatremic hypertensive syndrome (HHS)

Journal of Pediatric and Neonatal Individualized Medicine
A 2-year-9-month-old boy presented with renovascular hypertension caused by middle-segment stenosis of the right renal artery, and a severe hypertensive crisis, accompanied by hyponatremia, hypokalemia, and transient proteinuria. Fibromuscular dysplasia (
Asrar Abu Bakar, Sharifah Aishah Syed Ahmad Alsagoff, Muhamad Azamin Anuar, Ganeshwara Durai Raja Lingam   +3 more
doaj   +1 more source