Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Early Changes in Resting-State Connectivity of the Anterior Insular Cortex Are Associated with Reductions in Pain and Catastrophizing After Total Hip Arthroplasty in Female Patients: A Preliminary Study. [PDF]
Chuda Y +6 more
europepmc +1 more source
Selective methane (CH4) photooxidation emerges from architectural decoupling of activation and preservation. Programmable organic semiconductor frameworks spatially organize oxidative flux and intermediate residence, separating reaction zones from product domains to synchronize activation strength with stabilization and establish a selective oxidation ...
Minxian Zhang +5 more
wiley +1 more source
Facial Adipostructuring With Biochemical Modulation in Chronic Peripheral Facial Paralysis: A Case Report. [PDF]
Calfin H +4 more
europepmc +1 more source
Hybrid Amyloid–Boron Nitride Aerogels for Lightweight Sound Insulation
Amyloid fibrils template the mild formation of boron nitride–rich hybrid aerogels with hierarchical porosity, enhanced BN‐like ordering, and fibril‐reinforced mechanics. These ultralight materials combine thermal stability with strong sound absorption and transmission loss, offering a sustainable bio‐assisted route toward lightweight acoustic shields ...
Mohammad Peydayesh +8 more
wiley +1 more source
Electrical resistivity change upon annealing is introduced as a rapid descriptor for identifying high glass‐forming ability in metallic glasses. High‐throughput combinatorial thin‐film libraries reveal that compositions exhibiting small resistivity changes correspond to sluggish crystallization behavior and known bulk metallic glass regions, enabling ...
Haechan Jo +5 more
wiley +1 more source
Toward Reconciling the Standard Binding Free Energy of Lenacapavir to HIV-1 Capsid with Experiment: Thermodynamic Effects of Solvent Buffer and Ligand Reorganization. [PDF]
Sun Q, Gallicchio E, Levy R, Deng N.
europepmc +1 more source
Organic electrochemical synaptic transistors based on sidechain‐engineered conjugated polyelectrolytes reveal that cationic sidechains enable efficient volumetric ion penetration and dense backbone doping, leading to enhanced transconductance and long‐term synaptic retention.
Haim Kwon +6 more
wiley +1 more source
Decoupling Dynamics and Crosslink Stability in Supramolecular Hydrogels Using Associative Exchange. [PDF]
Le Bourdonnec P +4 more
europepmc +1 more source

