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Genome and evolution of Tibet orbivirus, TIBOV (genus Orbivirus, family Reoviridae) [PDF]
Tibet orbivirus (TIBOV) was first isolated from Anopheles maculatus mosquitoes in Xizang, China, in 2009. In recent years, more TIBOV strains have been isolated in several provinces across China, Japan, East Asia, and Nepal, South Asia.
Tingting Gao+5 more
doaj +2 more sources
Reovirus genomes are segmented, double-stranded RNA. Virions contain from 9 to 12 linear segments. Virions are unenveloped and capsids are constructed from two or three discrete protein layers. Upon entry into the cell, the outer capsid layer(s) disassemble but genome segments remain within the innermost core.
Susan Payne
openaire +3 more sources
Bluetongue virus VP1 polymerase activity in vitro: template dependency, dinucleotide priming and cap dependency. [PDF]
Bluetongue virus (BTV) protein, VP1, is known to possess an intrinsic polymerase function, unlike rotavirus VP1, which requires the capsid protein VP2 for its catalytic activity.
Eiko Matsuo, Polly Roy
doaj +7 more sources
Identification and molecular characterization of highly divergent RNA viruses in cattle, Uganda. [PDF]
The risk for the emergence of novel viral zoonotic diseases in animals and humans in Uganda is high given its geographical location with high biodiversity.
Stephen Balinandi+6 more
doaj +2 more sources
Comparative analysis of Reoviridae reverse genetics methods [PDF]
Effective methods to engineer the segmented, double-stranded RNA genomes of Reoviridae viruses have only recently been developed. Mammalian orthoreoviruses (MRV) and bluetongue virus (BTV) can be recovered from entirely recombinant reagents, significantly improving the capacity to study the replication, pathogenesis, and transmission of these viruses ...
Terence S. Dermody+3 more
openaire +4 more sources
A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro [PDF]
Background Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step.
Sabrina Weiss+4 more
doaj +4 more sources
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus [PDF]
Viruses in the Reoviridae, like the triple-shelled human rotavirus and the single-shelled insect cytoplasmic polyhedrosis virus (CPV), all package a genome of segmented double-stranded RNAs (dsRNAs) inside the viral capsid and carry out endogenous ...
Ke Ding, Xuekui Yu, Jingchen Sun
exaly +2 more sources
While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized.
Anna C Fagre+2 more
exaly +3 more sources
Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses [PDF]
Houssam Attoui+6 more
exaly +2 more sources