Results 141 to 150 of about 1,420,060 (248)
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node. [PDF]
FEBS Open BioThe circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Wagner PM +6 more
europepmc +2 more sources
La Ciropedia y los límites de la virtud política
Araucaria, 2017 El presente trabajo procura llevar a cabo una reflexión acerca de la virtud política y sus límites en la Ciropedia de Jenofonte. Nuestra lectura sostendrá que la Ciropedia es una reflexión implícita sobre la mejor forma de gobierno y su relación con la ...
Agustín Volco
doaj
Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation
The FEBS Journal, EarlyView.Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev +2 more
wiley +1 more source
La figura del maestro, en la Escuela de la República
Revista Interuniversitaria de Formación del Profesorado, 2002 Uno de los primeros objetivos de la República Española (1931) fue llevar a cabo un profundo proceso de modernización del sistema escolar, tanto en construcciones como en contenidos y mejoras profesionales. El director general, Rodolfo Llopis, que había
Clotilde Navarro García
doaj
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases
The FEBS Journal, EarlyView.Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek +12 more
wiley +1 more source
Historia y Memoria, 2012 A través de este texto se pretende analizar el discurso y las acciones de Vicente Guerrero en el marco del restablecimiento de la constitución española, quien en 1810 había iniciado una actividad militar exitosa para la toma del poder al lado de Morelos.
Eduardo Miranda Arrieta
doaj
Fisheries Management and Ecology, EarlyView.ABSTRACT Using pikeperch (Sander lucioperca) as a model species, we investigated the factors influencing fluctuations in the abundance of piscivorous intra‐annual cohorts and assessed the role of three distinct cohorts: extremely small (ES), ordinary (or mid‐sized) fingerlings, and piscivorous in shaping year‐class strength.
Million Tesfaye +21 more
wiley +1 more source
Historia y Memoria, 2012 Aunque sus textos suelen contener una porción mayor de aspiraciones que den realidades históricas tangibles, para los historiadores, otros humanistas y también los dedicados a las ciencias sociales, desde un punto de vista epistemológico las ...
Víctor Uribe Urán
doaj
La república democrática unitaria y la república federal [PDF]
Copia digital. Valladolid : Junta de Castilla y León.
García Ruiz, Eugenio, 1818-1883
core +1 more source
First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing
Journal of Fish Biology, EarlyView.Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley +1 more source