Results 141 to 150 of about 1,445,429 (293)
The FEBS Journal, EarlyView.We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher +7 more
wiley +1 more source
Los entramados de lo público: república, plebe, publicidad y población
Revista Colombiana de Antropología, 2015 En este ensayo propongo abordar de mane - ra integral las múltiples experiencias de lo público que se manifiestan, en buena parte de nuestras sociedades contemporáneas, aisladas y fracturadas, como si no tuvieran relación una con otra. La premisa es,
Francisco A. Ortega
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Moda masculina y distinción social. El ejemplo de Asturias desde la Restauración hasta la Segunda República<br /><em>Male fashion and social distinction. The example of Asturias from the Restoration to the Second Republic</em> [PDF]
, 2017 Luis Álvarez
openalex +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
Sons, Brothers and Relatives in the Entourages of the Roman Provincial Commanders during the Republic: A Characteristic Behaviour of the Roman Ruling Class [PDF]
, 2017 Durante la época de la República era una costumbre bien conocida que el cónsul o pretor destinado a una provincia se dotara de una serie de colaboradores y acompañantes que constituían la cohors o comitiva del imperator.
Díaz Fernández, Alejandro
core
Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation
The FEBS Journal, EarlyView.Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev +2 more
wiley +1 more source
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases
The FEBS Journal, EarlyView.Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek +12 more
wiley +1 more source
Fronteras de la Historia, 2012 En este artículo se señalan algunas ambivalencias del periodo de tránsito del régimen colonial al modelo republicano, en particular, la relativa a la disputa por las fuentes del derecho en el proceso de modernización institucional, la cual ha tenido ...
Diana Paola Herrera Arroyave
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