Results 251 to 260 of about 1,567,787 (319)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Lifetime management of primary mitral regurgitation through integrated surgical and transcatheter reinterventions. [PDF]

NPJ Cardiovasc Health
Tabata M.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Beyond morphometry: the atrial septal defect pressure gradient as a dynamic predictor of mitral valve growth in borderline left hearts. [PDF]

Clin Exp Pediatr
Park HK.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Open versus arthroscopic management of acute and chronic distal radioulnar joint instability: a systematic review and meta-analysis. [PDF]

BMC Musculoskelet Disord
Hegazy G, Hammouda AI, Ramadan M, Elzoghby A, Elzahed E, El-Sebaey I, Elgeushy A, Seddik M.   +7 more
europepmc   +1 more source

Management of Ulnar Collateral Ligament Injuries of the Elbow. [PDF]

Curr Rev Musculoskelet Med
Ryan PM, Beyer J, Hartman H, Ismail H, Alam M, DeFroda SF.   +5 more
europepmc   +1 more source

Novel use of endoscopic pigtail drainage in recurrent gastric perforation following intentional drug overdose: a case report. [PDF]

J Surg Case Rep
Dodangeh M, Kanani H, Soori M.
europepmc   +1 more source