Results 141 to 150 of about 251,710 (258)
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source
Immunoengineering External Field Responsive Biomaterials for Tissue Repair and Regeneration. [PDF]
Song W +6 more
europepmc +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Recent Advances in Diversified Materials for Spinal Cord Injury Repair and Regeneration. [PDF]
Wang Y +5 more
europepmc +1 more source
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
Sebaceous gland reprogramming with a single gene, PPARG, and small molecules
Yiqiong Liu +9 more
doaj +1 more source
Herbal polysaccharides-a rising star in engineering multifunctional biomaterials for tissue repair and regeneration. [PDF]
Huang R +6 more
europepmc +1 more source
Identification of molecular mechanisms underlying regeneration in vertebrate brains
In the adult zebrafish brain, life-long proliferation and neurogenesis occur in several ventricular stem cell zones. The widespread neurogenesis is associated with remarkable regenerative potential.
Svetlana Sirko +9 more
core
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk +11 more
wiley +1 more source

