Results 31 to 40 of about 17,320 (252)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
WAR REPARATIONS: POLISH EXPERIENCE AND UKRAINIAN PROSPECTS [PDF]
Alfred Nobel University Journal of LawThe article examines the problem of Ukraine collecting war reparations from the Russian Federation. A few years ago, it seemed that the problem of collecting war reparations concerned only the consequences of the Second World War and would certainly ...
Ivan M. Pankevych
doaj +1 more source
Reparations in the Caribbean and Diaspora
Caribbean Quilt, 2020 Millions of people have been victim to violent and inhumane social injustices, many of them based on racial and cultural hierarchies. The Nazi Holocaust or the colonization of North America through the genocide of indigenous populations are examples of ...
Prilly Bicknell-Hersco
doaj +1 more source
Igniting Pathways for Land-Based Healing: Possibilities for Institutional Accountability
Genealogy, 2023 U.S. based post-secondary educational institutions usually have violent origin stories that include land theft, genocide, and the participation in slavery. Schools of social work are no exception.
Diana Melendez +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Les temps et les modes des politiques réparatrices
Temporalités, 2015 This article focuses on the perception of time in the aftermath of mass violence. It demonstrates that reparative measures taken in order to do justice and to establish a dialogue between groups affected by past crimes have an influence on the way time ...
Joëlle Hecker
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source