Results 31 to 40 of about 2,882 (209)

Follicular growth patterns in repeat breeder cows

open access: yesVeterinární Medicína, 2003
The aim of this study was to examine follicular development patterns in eighteen repeat breeder cows through natural oestrus cycles. Ovarian ultrasonographic examinations over 32 days after artificial insemination revealed that two follicular waves were ...
C.C. Pérez   +5 more
doaj   +1 more source

SOME MICROELEMENTS PROFILE IN CYCLIC NON-BREEDING COW SYNDROME (REPEAT BREEDER) [PDF]

open access: yesAssiut Veterinary Medical Journal, 1993
SUMMEARY The present study was conducted to elucidate serum profile of some microelements (copper, zinc, selenium and manganese) in cyclic non-breeding (CNB) dairy cows.
M.A. EL-AZAB   +3 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

IN4MER Biomaterial Ink: A Phosphorescent Biosensing Biomaterial Ink for Multiple Analytes (Glucose, Lactate, Oxygen) Measurements and Temperature Sensing Applications

open access: yesAdvanced Functional Materials, EarlyView.
Multianalyte, real‐time monitoring of bioprinted scaffolds remains challenging. Phosphorescence‐lifetime–based, optically responsive microparticles are embedded in diverse printable hydrogels (κ‐carrageenan, GelMA, PEGDA) to form biomaterial inks that report oxygen, glucose, lactate, and temperature.
Waqas Saleem   +11 more
wiley   +1 more source

Characterisation of the Repeat Breeding Syndrome in Swedish Dairy Cattle

open access: yesActa Veterinaria Scandinavica, 2002
Repeat breeding (RB), defined as cows failure to conceive from 3 or more regularly spaced services in the absence of detectable abnormalities, is a costly problem for the dairy producer.
Emanuelson U, Gustafsson H
doaj   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

HAEMATO-BIOCHEMICAL PROFILE IN REPEAT BREEDING CROSS-BRED COWS [PDF]

open access: yesExploratory Animal and Medical Research, 2012
A total of 18 lactating multiparous cows (4-6 years aged) were selected from the out patients at the Addl. Block Animal Health Center, Matiali Block, Jalpaiguri, West Bengal, India and divided into three group, i.e normally cyclic (C), repeat breeder ...
Manas Kr. Mondal, Samik Kr. Paul
doaj  

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

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