Results 51 to 60 of about 2,882 (209)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

PHYSICAL CHARACTERISTICS OF OESTRUS MUCUS AND CONCEPTION RATES IN REPEAT BREEDER BUFFALOES

Pakistan Veterinary Journal, 2002
A project was planned to study some physical characteristics of oestrus mucus and conception rates in repeat breeder buffaloes after different treatments. For this purpose 60 adult buffaloes with history of repeat breeding were used.
H.A. Samad. S.M. Iqbal Shah. Nazir Ahmad and Nafees Akhtar
doaj   +2 more sources

Major reproductive health problems of indigenous Borena cows in Ethiopia

Journal of Advanced Veterinary and Animal Research, 2014
The study was conducted to identify the major reproductive health problems and its associated risk factors in indigenous Borena breed cows in Borena zone in Southern Ethiopia between September 2013 and February 2014.
Ararsa Duguma Benti, Wubishet Zewdie
doaj   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

Prevalence and Risk Factor of Repeat Breeder Syndrome in Dairy Cows in KUD Bebarengan Anggayuh Tentrem Urip, Batu City, East Java Province

Media Kedokteran Hewan
This study aims to contribute valuable insights to readers and serve as a reference for dairy farmers looking to enhance their operations. By examining the prevalence and risk factors associated with repeat breeder syndrome in dairy cows within the ...
Frida Aulya Arningdiah, Aldin Akbar Rahmatullah, Cindy Ercha Aulia Putri, Mufasirin, Hermin Ratnani, Rimayanti, Sri Pantja Madyawati, Tita Damayanti Lestari, Muhammad Al-Syafiq bin Abdul Halim, Nuurin Ajrin Karim   +9 more
doaj   +1 more source

Pregnancy Rates in Repeat-breeder Heifers Following Multiple Artificial Inseminations during Spontaneous Oestrus

Acta Veterinaria Scandinavica, 2005
Hormonal asynchronies during oestrus, related to the presence of suprabasal plasma-progesterone (P4) concentrations and a delayed ovulation, interfere with the fertility of repeat-breeder heifers (RBH).
Rodríguez-Martínez Heriberto, Båge Renée, Saravia Fernando, Singh Bhupender   +3 more
doaj   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Effect of Oxytocin and Cofecu on Post Insemination conception rate in repeat breeder cattle on subsequent time interval [PDF]

Veterinary World, 2008
Fifty cross bred repeat breeder cattle belonging to farmers from different villages around the Veterinary College during the period from January 2006 to December 2006 were divided into five group. All animals were between 3 and 6 year. All groups treated
D.Mahto, B.Singh, A. Adil and R.K. Verma
doaj