Results 61 to 70 of about 264,015 (173)

A CT Lesion Foundation Model for Non‐Invasive Assessment of Hepatocellular Carcinoma Aggressiveness and Prediction of Recurrence Risk

Advanced Science, EarlyView.
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia, Zhehan Shen, Mengsi Li, Jianxin Lu, Ji Xia, Yang Cheng, Wenzheng Li, Shunjie Dong, Lin Deng, Ruokun Li   +9 more
wiley   +1 more source

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe, Junya Mita, Shinji Itoh, Takeo Toshima, Yoshiyuki Kitamura, Norifumi Iseda, Takuro Isoda, Kousei Ishigami, Tomoharu Yoshizumi   +8 more
wiley   +1 more source

Efficacy of treatment based on TKIs in combination with PD-1 inhibitors for unresectable recurrent hepatocellular carcinoma

World Journal of Surgical Oncology, 2023
Background and objective The recurrence occurs within 5 years in up to 70% of hepatocellular carcinoma (HCC) patients who received radical liver resection, and most patients are no longer suitable for repeat surgery.
Ze Zhang, Tianyu Jiao, Junfeng Li, Bingyang Hu, Wenwen Zhang, Zhijun Wang, Tao Wan, Yafei Wang, Shichun Lu   +8 more
doaj   +1 more source

Biological Resectability in Colorectal Liver Metastases: A Nomogram‐Based Continuous Risk Model to Define Borderline Disease

Annals of Gastroenterological Surgery, EarlyView.
KRAS mutation demonstrated a prognostic impact according to primary tumor sidedness, independent of tumor morphology, in patients undergoing hepatectomy for colorectal liver metastases. A nomogram integrating biological and clinicopathological factors was developed to provide continuous biological risk assessment.
Yuzo Umeda, Toshiharu Mitsuhashi, Tomokazu Fuji, Toru Kojima, Takeshi Koujima, Tatsuo Matsuda, Daisuke Satoh, Masaru Inagaki, Kosei Takagi, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

A case of pancreaticoduodenectomy and partial hepatic resection as repeat cytoreductive surgery for recurrent pseudomyxoma peritonei

Surgical Case Reports, 2021
Background For recurrent pseudomyxoma peritonei (PMP), repeat cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) can provide survival benefits if patients are carefully selected.
Kenya Yamanaka, Norishige Iizuka, Toshiyuki Kitai   +2 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Combined radiofrequency ablation and ethanol injection versus repeat hepatectomy for elderly patients with recurrent hepatocellular carcinoma after initial hepatic surgery

, 2018
Purpose: To retrospectively compare the efficacy and safety of combined radiofrequency ablation and percutaneous ethanol injection (RFA–PEI) with repeat hepatectomy for elderly patients with initial recurrent hepatocellular carcinoma (HCC) after hepatic ...
Wenjie Hu (2698855), Han Xiao (373894), Chunlin Jiang (4283191), Ming Kuang (1522798), Manxia Lin (5710844), Shuling Chen (621838), Xiaoyan Xie (38028), Zhenwei Peng (389483), Longzhong Liu (5710847), Zebin Chen (3925220), Baogang Peng (5710850)   +10 more
core   +1 more source

Central hepatectomy versus major hepatectomy for patients with centrally located hepatocellular carcinoma: a systematic review and meta-analysis

BMC Surgery, 2023
Background and aim For those with a centrally located HCC, the two types of liver sectionectomy that can be performed are extended hepatectomy (EH) and central hepatectomy (CH).
Edward Atef Gadallah, Beshoy Effat Elkomos, Ahmed Khalil, Fawzy Salah fawzy, Amr Abdelaal   +4 more
doaj   +1 more source

Repeat-masked genome

, 2021
Repeat-masked genome ...
Jianfeng Jin (11709806)
core   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source