Results 81 to 90 of about 264,015 (173)

The Effectiveness of Prehabilitation on Surgical Outcomes in Pancreatic Surgery: A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Pancreatic surgery is associated with high rates of postoperative complications. Prehabilitation has emerged as a key preoperative strategy to optimize patients’ physiological status prior to surgery. However, its specific role and efficacy in pancreatic surgery is not well established.
Lyrics M. Noba, Robyn J. Stiger, Sanjay Pandanaboyana, Christopher J. Gaffney, Lawrence D. Hayes, Michael P. W. Grocott, Ajith K. Siriwardena   +6 more
wiley   +1 more source

Case Report: A giant cavernous hemangioma detected in the remnant left liver 33 months after laparoscopic liver resection

Frontiers in Medicine
A giant hepatic hemangioma detected after resection raises questions about lesion continuity and resection completeness. A 50-year-old man underwent laparoscopic resection in January 2022 for a symptomatic 10.0 × 7.8 cm cavernous hemangioma.
Hongxiao Liu, Hongxiao Liu, Yaoping Pang, Haoyun Min, Zhendong Fu, Guanwei Gao, Guanwei Gao, Zhouyu Gao, Zhouyu Gao, Meng Li, Meng Li, Jianwei Qin   +11 more
doaj   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Repeat hepatectomy versus thermal ablation therapy for recurrent hepatocellular carcinoma: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundThis meta-analysis was conducted to assess the survival benefits of repeat hepatectomy (RH) and thermal ablation therapy (TAT) in managing recurrent hepatocellular carcinoma (HCC).MethodsA comprehensive search was conducted in the PubMed ...
Renhua Dong, Ting Zhang, Wenwu Wan, Hao Zhang   +3 more
doaj   +1 more source

Assessment of MRD and Longitudinal Monitoring of Post‐Surgery Biliary Tract Cancer With a Customized ctDNA Panel

Cancer Science, EarlyView.
A customized panel was established for BTC MRD detection. Preoperative ctDNA detection was associated with pathological stage and poorer RFS and OS. Longitudinal monitoring detected ctDNA before radiological recurrence in 72.7% of patients, with a median lead time of 77 days, supporting ctDNA as a complementary prognostic biomarker with CA19‐9 ...
Yoshihito Shinohara, Toru Nakamura, Yasutoshi Kimura, Takeshi Murakami, Shigeyuki Kojima, Toshikazu Yamaguchi, Kanako C. Hatanaka, Ryo Okazaki, Yosuke Kitayama, Keita Fukuda, Fabio Pittella‐Silva, Yusuke Nakamura, Satoshi Hirano, Siew‐Kee Low   +13 more
wiley   +1 more source

Hepatocellular Carcinoma: Current Management and Future Development—Improved Outcomes with Surgical Resection

International Journal of Hepatology, 2011
Currently, surgical resection is the treatment strategy offering the best long-term outcomes in patients with hepatocellular carcinoma (HCC). Especially for advanced HCC, surgical resection is the only strategy that is potentially curative, and the ...
Yoji Kishi, Kiyoshi Hasegawa, Yasuhiko Sugawara, Norihiro Kokudo   +3 more
doaj   +1 more source

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins [PDF]

, 2014
An expanded GGGGCC repeat in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. A fundamental question is whether toxicity is driven by the repeat RNA itself and/or by dipeptide repeat proteins ...
Ridler, CE, Pickering-Brown, Stuart, Norona, FE, Woollacott, I., Fratta, P., Norona, Frances E, Woollacott, IOC, Ridler, Charlotte E, Devoy, A, Pietrzyk, J, Fisher, EMC, Devoy, Anny, Dols, J, Dols, Jacqueline, Moens, T., Cleverley, K., Fratta, Pietro, Partridge, Linda, Nicoll, Andrew J, Fisher, E., Ridler, C., Fratta, P, Grönke, S., Pickering-Brown, S., Isaacs, Adrian M, Cabecinha, Melissa, Mizielinska, S, Moens, Thomas, Clayton, E., Partridge, L., Pietrzyk, J., Clayton, Emma L, Mizielinska, Sarah, Niccoli, T., Devoy, Anny; id_orcid, Mizielinska, Sarah; id_orcid, Isaacs, A., Woollacott, Ione O C, Cleverley, Karen, Nicoll, AJ, Hendrich, O., Moens, T, Dols, J., Grönke, Sebastian, Cabecinha, M., Cabecinha, M, Fisher, Elizabeth M C, Mizielinska, S., Clayton, EL, Nicoll, A., Hendrich, Oliver, Grönke, S, Niccoli, Teresa, Pietrzyk, Julian, Devoy, A., Norona, F., Isaacs, AM, Pickering-Brown, S, Cleverley, K, Hendrich, O, Niccoli, T, Partridge, L   +61 more
core   +1 more source

NEDD4 Promotes Hepatocellular Carcinoma Progression Through Ubiquitin‐Dependent Degradation of EPHB6

Cancer Science, EarlyView.
NEDD4 drives K48‐linked polyubiquitination and proteasomal degradation of EPHB6, activating TGF‐beta SMAD2/3 signaling and upregulating EMT markers to promote tumor progression. ABSTRACT Neural precursor cell expressed developmentally down‐regulated 4 (NEDD4) has been implicated in the progression of various human malignancies, including hepatocellular
Guowei Zhang, Mengxuan Ji, Zhiyi Liu, Jiawei Xu, Qinghe Hu, Xue Zhang, Jie Qiu, Kai Wu, Bin Zhang, Yi He, Hengliang Shi   +10 more
wiley   +1 more source

Impact of diabetes mellitus on the prognosis of patients with hepatocellular carcinoma after curative hepatectomy.

PLoS ONE, 2014
BackgroundThe influence of diabetes mellitus (DM) on the prognosis of patients with hepatocellular carcinoma (HCC) remains controversial. Here we investigated the impact of DM on the prognosis of such patients after curative hepatectomy.MethodsA ...
Yan-Yan Wang, Shan Huang, Jian-Hong Zhong, Yang Ke, Zhe Guo, Jia-Qi Liu, Liang Ma, Hang Li, Bing-Ning Ou, Le-Qun Li   +9 more
doaj   +1 more source

Effectiveness of Laparoscopic Repeat Hepatectomy for Recurrent Liver Cancer

Journal of Nippon Medical School, 2019
Patients with recurrent hepatocellular carcinoma or metastatic liver cancer from colorectal cancer after surgical resection have traditionally been treated with conventional open surgery. However, recent technical advances have facilitated laparoscopic repeat hepatectomy (LapRH), which has advantages over open laparotomy.
Yoshioka, Masato, Taniai, Nobuhiko, Kawano, Youichi, Shimizu, Tetsuya, Kondo, Ryota, Kaneya, Yohei, Aoki, Yuto, Yoshida, Hiroshi   +7 more
openaire   +3 more sources