Results 111 to 120 of about 415,868 (306)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Generic Techniques for the Calibration of Robots with Application of the 3-D Fixtures and Statistical Technique on the PUMA 500 and ARID Robots [PDF]
A relatively simple, inexpensive, and generic technique that could be used in both laboratories and some operation site environments is introduced at the Robotics Applications and Development Laboratory (RADL) at Kennedy Space Center (KSC).
Tawfik, Hazem
core +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Repeatability, accuracy, portability, and errors of the portable alignment gyrocompass system [PDF]
Portable alignment gyrocompass system accuracy, repeatability, portability, and ...
Mihm, J. J., Murphy, R. A.
core +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Agreement between two successive transvaginal salpingosonography assessments of tubal patency
Objective. To evaluate the agreement between repeat transvaginal sonographic assessments of tubal patency using a combination of air and saline. Material and methods. Twenty‐nine patients were examined twice by the same investigator (H.S.).
Aydin Tekay +3 more
doaj +1 more source
Salient Regions for Query by Image Content
Much previous work on image retrieval has used global features such as colour and texture to describe the content of the image. However, these global features are insufficient to accurately describe the image content when different parts of the image ...
Hare, Jonathon S., Lewis, Paul H.
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
What makes for effective detection proposals?
Current top performing object detectors employ detection proposals to guide the search for objects, thereby avoiding exhaustive sliding window search across images.
Benenson, Rodrigo +3 more
core +1 more source

