Results 121 to 130 of about 70,193 (268)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Repeatability or reproducibility in Australian Patent Law

, 2014
This article considers the extent to which a claimed process must be repeatable or reproducible in order to be patentable according to Australian patent law.
McEniery, Benjamin J.
core  

Cycloplegia Improves the Inter-Optometrist Repeatability of Subjective Refraction

Background: Since accommodation may be a source of error affecting the inter-optometrist repeatability of subjective refraction, this study investigated whether the use of cycloplegia could improve this repeatability.
Ana Privado-Aroco, Carracedo Rodríguez, Juan Gonzalo, Laura Batres, Carlos Carpena-Torres, Privado Aroco, Ana, Cristina Pastrana, Batres Valderas, Laura, Gonzalo Carracedo, María Serramito, Serramito Blanco, María, Carpena Torres, Carlos, Pastrana Robles, Cristina, Maria Rodríguez-Lafora, Rodríguez-Lafora Lorente, María   +13 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Phenotypic stability and genetic gains in six-year girth growth of Hevea clones Estabilidade fenotípica e ganhos genéticos de seis anos de avaliação do perímetro do caule em clones de seringueira

Pesquisa Agropecuária Brasileira, 1999
Rubber tree [Hevea brasiliensis (Willd. ex Adr. de Juss.) Müell. Arg.] budgrafts of seven clones were evaluated on five contrasting sites in the plateau region of the São Paulo State, Brazil.
Paulo de Souza Gonçalves, Alberto Kazutoshi Fujihara, Altino Aldo Ortolani, Ondino Cleante Bataglia, Nelson Bortoletto, Ivo Segnini Junior   +5 more
doaj  

Repeatability and Comparison of Keratometry Values Measured with Potec PRK-6000 Autorefractometer, IOLMaster, and Pentacam

, 2014
Objectives: To research the repeatability and intercompatibility of keratometry values measured with Potec PRK-6000 autorefractometer, IOL Master, and Pentacam.
Ceyhun Arıcı, Mehmet Kola, Osman Melih Ceylan, Adem Türk   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Flexible Calibration Method and Application of Passenger Car HUD Detection Based on Collaborative Robot

IEEE Access
At present, the HUD calibration of the whole vehicle enterprise adopts the traditional physical Master Gauge to calibrate the camera, and the scheme has low flexibility, occupies a large space, and is unsuitable for the mixed production of different ...
Ding Zhigang, Yanlu Lv, Linghua Kong, Zhiming Dong, Jishi Zheng, Jiadi Zhang, Jiaxin Liu   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Repeatability and corrected repeatability of posterior corneal elevation.

, 2019
(a) Repeatability (red) and corrected repeatability (black) of posterior corneal elevation data maps obtained with Pentacam AXL and (b) CASIA 2 (right) averaged along concentric rings ± standard deviation (shaded area) as a function of the radial ...
Achim Langenbucher (3156741), Simon Schröder (3156735), Jens Schrecker (7507826)   +2 more
core   +1 more source