Results 121 to 130 of about 861,022 (290)

Strengthening of Deficient Drop-in-ends with Near Surface Mounted (NSM) Steel Bars under static and repeated loading

Journal of Materials and Engineering Structures
The present research work, presented the results of eight drop-in-ends specimens tested experimentally to investigate the efficiency of the NSM steel bars technique in strengthening the drop-in-ends including internal miss detailing, under static and ...
Qasim Muhammed SHAKIR, Ruqyia ALLIWE
doaj  

RESPONSE OF LACED REINFORCED CONCRETE BEAMS SUBJECTED TO REPEATED LOADING

Journal of Engineering and Sustainable Development, 2018
In this research, the structural behavior of Laced Reinforced Concrete T-beam of cross sectional dimensions (300mm × 80mm) flange and (150mm × 220mm) web under monotonic loadings was studied experimentally.
Abbas AbdulMajeed Allawi, Arshad Nadhom Mohammed Ali Shubber   +1 more
doaj  

Compression properties of polymeric syntactic foam composites under cyclic loading

, 2019
Syntactic foams are composite materials frequently used in applications requiring the properties of low density and high damage tolerance. In the present work, polymer-based syntactic foams were studied under cyclic compression in order to investigate ...
Parnell, W. J., Potluri, P., Smith, M. J. A., Yousaf, Z.   +3 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Evaluating the interaction for embedded H-steel section in normal concrete under monotonic and repeated loads

Open Engineering
This article presents an experimental investigation into alternative strategies for enhancing the interaction of H-shaped steel sections embedded in normal reinforced concrete.
Al-Jafal Alaulddin A., Al-Darzi Suhaib Y.   +1 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Response of Laced Reinforced Concrete One Way Slab to Repeated Loading

Journal of Engineering, 2016
Test results of nine reinforced concrete one way slab with and without lacing reinforcement are reported. The tests were designed to study the effect of the lacing reinforcement on the flexural response of one way slabs.
Abaas Abdulmajeed Allawi, Hussain Askar Jabir   +1 more
doaj   +2 more sources

Repeated Load Permanent Deformation Behavior of Mixes With and Wihtout Modified Bituments [PDF]

Mehran University Research Journal of Engineering and Technology, 2011
Premature rutting in flexible pavement structure is being observed on most of the road network of Pakistan. It initiates primarily due to uncontrolled axle loading and high ambient temperatures.
Imran Hafeez, Mumtaz Ahmed Kamal
doaj  

Strength calculation for a tank of the tank-car under repeated loading [PDF]

, 2006
В данной работе выполнена оценка усталостной прочности котла вагона- цистерны при циклическом нагружении на основании прочностного расчета, определен характер изменения во времени основных нагрузок и их влияние на появление усталостных трещин котла ...
Boyko, A., Kononova, O., Бойко, А., Кононова, О.   +3 more
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