Revista Colombiana de Estadística, 2012 A strategy for the construction of anthropometric indicators employed for the evaluation of the pregnant women’s nutritional state is presented. The references of weight by pregnancy week, according to height and the body mass index at the beginning of ...
Montero Minerva +4 more
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Answer for questions of repeated measurements of variance analysis and distribution test of data - Authors' reply. [PDF]
Front Med, 2022 Wang DW, Ni L, Jiang H.
europepmc +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Repeated Measurements Are Necessary for Evaluating Accurate Diurnal Rhythm Using a Self-Intraocular Pressure Measurement Device. [PDF]
J Clin Med, 2023 Shigemoto Y +7 more
europepmc +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
The use of randomization in repeated measurements
It is shown that randomization applies in repeated measurements whenever the F-test applies in the analysis. Contrary to common practice, randomization otherwise invalidates the use of Hotelling's T2 and Box's approximate test, and it presents ...
Jensen, D. R.
core
Using Automated Speech Processing for Repeated Measurements in a Clinical Setting of the Behavioral Variability in the Stroop Task. [PDF]
Brain Sci, 2023 Holmlund TB +7 more
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Concordance rate of a four-quadrant plot for repeated measurements. [PDF]
BMC Med Res Methodol, 2021 Hiraishi M, Tanioka K, Shimokawa T.
europepmc +1 more source