Results 151 to 160 of about 4,658,486 (302)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

TWO-SAMPLE TESTS FOR MULTIVARIATE REPEATED MEASUREMENTS OF HISTOGRAM OBJECTS WITH APPLICATIONS TO WEARABLE DEVICE DATA. [PDF]

Ann Appl Stat, 2022
Zhang J, Merikangas KR, Li H, Shou H.
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Análisis de la evolución en el tiempo para datos con estructura de grupos: STATIS dual canónico y modelo de medidas repetidas doblemente multivariantes Analysis of Time Evolution for Group Structured Data: Canonical Dual STATIS and Doubly Multivariate Repeated Measures Model

Revista Colombiana de Estadística, 2008
En este trabajo proponemos dos soluciones al problema que se plantea cuando se pretende analizar datos multivariantes, para un conjunto de individuos con estructura de grupos, que además han sido replicados bien sea en ocasiones o en situaciones ...
AMPARO VALLEJO, JOSÉ LUIS VICENTE, PURIFICACIÓN GALINDO, MARGARITA FERNÁNDEZ, CAMINO FERNÁNDEZ, ELOY BÉCARES   +5 more
doaj  

Short-Term Exposure to PM_2.5 and O₃ Impairs Liver Function in HIV/AIDS Patients: Evidence from a Repeated Measurements Study. [PDF]

Toxics, 2023
Ma H, Zhang Q, Liang W, Han A, Xie N, Xiang H, Wang X.   +6 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Association of longitudinal repeated measurements of frailty index with mortality: Cohort study among community-dwelling older adults. [PDF]

EClinicalMedicine, 2022
Li X, Schöttker B, Holleczek B, Brenner H.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Circular balanced uniform repeated measurements designs, II

Circular balanced uniform repeated measurements designs, which have been shown to be universally optimal by Kunert (1984), are constructed whenever the number of treatments is an odd number.Repeated measurements designs circular balanced uniform designs ...
Afsarinejad, Kasra
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