Results 1 to 10 of about 4,206,856 (305)

Multivariable association discovery in population-scale meta-omics studies.

open access: yesPLoS Computational Biology, 2021
It is challenging to associate features such as human health outcomes, diet, environmental conditions, or other metadata to microbial community measurements, due in part to their quantitative properties. Microbiome multi-omics are typically noisy, sparse
Himel Mallick   +19 more
doaj   +1 more source

Optimal Repeated Measurements for Two Treatment Designs with Dependent Observations: The Case of Compound Symmetry

open access: yesMathematics, 2019
In this paper, we construct optimal repeated measurement designs of two treatments for estimating direct effects, and we examine the case of compound symmetry dependency.
Miltiadis S. Chalikias
doaj   +1 more source

Power and sample size analysis for longitudinal mixed models of health in populations exposed to environmental contaminants: a tutorial

open access: yesBMC Medical Research Methodology, 2023
Background When evaluating the impact of environmental exposures on human health, study designs often include a series of repeated measurements. The goal is to determine whether populations have different trajectories of the environmental exposure over ...
Kylie K. Harrall   +6 more
doaj   +1 more source

Age-related decline in peak oxygen uptake: Cross-sectional vs. longitudinal findings. A review

open access: yesInternational Journal of Cardiology. Cardiovascular Risk and Prevention, 2023
Cardiorespiratory fitness is established as an important prognostic factor for cardiovascular and general health. In clinical settings cardiorespiratory fitness is often measured by cardiopulmonary exercise testing determining the gold-standard peak ...
Jon Magne Letnes   +2 more
doaj   +1 more source

An Overview on Method of Cyclic Shifts for the Construction of Experimental Designs Useful in Business and Commerce [PDF]

open access: yesPakistan Journal of Commerce and Social Sciences, 2020
The competitive nature of business today requires the knowledge to be able to manipulate process levels in a predictable fashion and to reduce process variation (quality control). This goal can be achieved through the use of experimentation to identify
Rashid Ahmed   +3 more
doaj  

Discriminant analysis for repeated measures data: a review

open access: yesFrontiers in Psychology, 2010
Discriminant analysis (DA) encompasses procedures for classifying observations into groups (i.e., predictive discriminative analysis) and describing the relative importance of variables for distinguishing amongst groups (i.e., descriptive discriminative ...
Lisa Lix, Tolulope Sajobi
doaj   +1 more source

Assessment of a Modified Sandwich Estimator for Generalized Estimating Equations with Application to Opioid Poisoning in MIMIC-IV ICU Patients

open access: yesStats, 2021
Longitudinal data is encountered frequently in many healthcare research areas to include the critical care environment. Repeated measures from the same subject are expected to correlate with each other.
Paul Rogers, Julie Stoner
doaj   +1 more source

INTRA-SCLERAL PARATHALAMUS IMPLANT: EFFICACY AND SAFETY IN RABBIT EYES

open access: yesActa Medica, 2014
Purpose: A variety of anti-glaucomatous shunt designs have been proposed so far. This study evaluates the feasibility of a novel shunt design, the intra-scleral parathalamus implant (IPI), in a rabbit eye model.
Efstathios T. Detorakis   +3 more
doaj   +1 more source

MCMSeq: Bayesian hierarchical modeling of clustered and repeated measures RNA sequencing experiments

open access: yesBMC Bioinformatics, 2020
Background As the barriers to incorporating RNA sequencing (RNA-Seq) into biomedical studies continue to decrease, the complexity and size of RNA-Seq experiments are rapidly growing.
Brian E. Vestal   +5 more
doaj   +1 more source

Misspecification in Generalized Linear Mixed Models and Its Impact on the Statistical Wald Test

open access: yesApplied Sciences, 2023
Generalized linear mixed models are commonly used in repeated measurement studies and account for the dependence between observations obtained from the same experimental unit.
Diana Arango-Botero   +2 more
doaj   +1 more source

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