Results 171 to 180 of about 4,653,774 (301)

Perceived empathy and competence across psychotherapist appearance types: a quasi-experimental repeated-measures study. [PDF]

Front Psychiatry
Festl-Wietek T, Le Guellec J, Erschens R, Albrecht T, Herrmann B, Zipfel S, Herrmann-Werner A.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Psychological and physiological moderators of perceived exertion in aerobics: a repeated-measures study. [PDF]

Front Psychol
Gao X, Zhao J, Zhao T, Song YG, Zhi Y, He X.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Position-Specific Match Demands in Professional Soccer Assessed Using GPS Technology: A Repeated-Measures Analysis. [PDF]

Sports (Basel)
Papadopoulos E, Vardakis L, Papadopoulou M, Papadopoulos K, Katsikas S, Tsentidou G.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of a Lumbar Support Cushion in a Backpack on Postural Alignment and Skeletal Muscle Mechanical Properties: A Repeated-Measures Trial in Healthy Adults. [PDF]

J Clin Med
Jung JY, Jung JH, Cho HY, Baek JE, Suh HR.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Correction: Acute psychological responses to formal and small-sided volleyball games in male youth athletes: an exploratory repeated-measures study. [PDF]

Front Psychol
do Nascimento MH, de Sá Filho AS, Aprigliano V, Clemente FM, Vieira CA, Campos MH, Rocha ACR, Arantes DDLC, Praça GM, Freire AB, Kawczyński A, Noll M, Costa GCT.   +12 more
europepmc   +1 more source