Results 191 to 200 of about 2,746,581 (301)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Promoting agency and communication through powered mobility: a single-group, repeated measures intervention using the explorer mini in toddlers with motor disabilities. [PDF]

Front Rehabil Sci
Gijbels L, Ingraham KA, Zaino NL, Hoffman ME, Mizrahi JC, Sinclair AN, Woo BY, Fragomeni A, Meltzoff AN, Steele KM, Feldner HA, Kuhl PK.   +11 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Understanding missed nursing care through felt accountability focus and task complexity: A prospective repeated-measures field study. [PDF]

Int J Nurs Stud Adv
Suliman L, Zahavy AD, Goldblatt H, Admi H, Peterfreund I, Sabah L, Srulovici E.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

VReeze: an open-source virtual reality for the examination of freezing of gait in Parkinson's disease - a study design of a crossover repeated measures study for validation. [PDF]

BMJ Open
Siragy T, Russo Y, Hirschbichler S, Nantel J, Wegscheider P, Schweiger H, Simonlehner M, Kisiel M, Horsak B.   +8 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Multivariate Bayesian Dynamic Borrowing for Repeated Measures Data With Application to External Control Arms in Open-Label Extension Studies. [PDF]

Biom J
Hartley BF, Psioda MA, Mander AP.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Changes in Workplace Productivity and Estimated Cost Savings During Internet-Based Cognitive Behavioral Therapy in the Irish National Health Service: Naturalistic, Repeated-Measures, Retrospective Survey Study. [PDF]

J Med Internet Res
Lee CT, Harty S, Enrique A, Jiménez-Díaz A, Hisler G, Duffy D, Richards D.   +6 more
europepmc   +1 more source