Results 311 to 320 of about 185,231 (352)

Reperfusion Therapies for Acute Ischemic Stroke

Current Treatment Options in Neurology, 2010
Ischemic stroke is most often caused by an acute extracranial or intracranial thromboembolic lesion obstructing an artery. It has been demonstrated that recanalization is the most important modifiable predictor of a good clinical outcome. Reperfusion strategies focus on early reopening of the vessel to reestablish antegrade flow within the penumbra ...
David, Goldemund, Robert, Mikulik
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Therapy Against Reperfusion-induced Microvascular Injury

Current Pharmaceutical Design, 2013
No-reflow, i.e., the lack of distal myocardial perfusion to fully recover following recanalization of an acutely occluded coronary artery, is not only a mere consequence of ischemic injury, as substantial microvascular alterations may also develop subsequently, after initial restoration of perfusion.
TRITTO, Isabella, ZUCHI, CINZIA, VITALE, SERENA, AMBROSIO, Giuseppe   +3 more
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Reperfusion therapy in acute cerebrovascular syndrome

Current Opinion in Neurology, 2011
Modern reperfusion therapy in acute ischemic stroke therapy is based on an 'as fast as possible' recanalization approach to obtain favorable clinical outcomes. However, arterial recanalization may be achieved without favorable clinical outcome, raising the question of the target population to be treated.
Mikael, Mazighi, Pierre, Amarenco
openaire   +2 more sources

Pharmacological therapy for myocardial reperfusion injury

Current Opinion in Pharmacology, 2004
In the ischemic myocardium, reperfusion is necessary for the salvage of cells and cardiac function. However, reperfusion itself causes 'reperfusion injury', leading to the damage of myocardial cells. This is reduced by several interventions, as measured by the limitation of infarct size or reduction of arrhythmias.
George V, Moukarbel, Chakib M, Ayoub, Antoine B, Abchee   +2 more
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Neurocytoprotection advances in reperfusion therapy

S.S. Korsakov Journal of Neurology and Psychiatry
Acute stroke is the second leading cause of death and the third leading cause of disability in the world. Ischemic stroke (IS) the most common type of stroke. In acute cerebral ischemia, damage to the brain tissue is complex and includes blood-brain barrier (BBB) dysfunction, neuroinflammation, oxidative stress, activation of intracellular and ...
I.A. Shchukin, I.A. Koltsov, M.S. Fidler, A.P. Glukhareva   +3 more
openaire   +2 more sources

Reperfusion Therapies in Acute Ischemic Stroke

Recent Patents on CNS Drug Discovery, 2015
Acute Ischemic stroke (IS) remains a leading cause of mortality and long-term disability. Owing to the time-constraints, only a fraction of acute IS patients receive the established and approved thrombolytic therapy and a sizeable proportion of acute IS stroke survivors remain permanently disabled.
Leonard L L, Yeo, Benjamin Y Q, Tan, Wan, Yee, Amit, Kulkarni, Vijay K, Sharma   +4 more
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Revascularization and reperfusion therapy

2008
This chapter focuses on revascularization and reperfusion therapy in the setting of ACS. Revascularization therapy is distinct from reperfusion therapy. The former takes place in non-ST-elevation or ST-elevation ACS, while reperfusion is employed only for ST-elevation myocardial infarction.
Anthony A Bavry, Deepak L Bhatt
openaire   +1 more source

Reperfusion Therapy for Acute Vertebrobasilar Occlusion

Interventional Neuroradiology, 1997
We reviewed retrospectively our experience in treating 10 patients with acute vertebrobasilar occlusion. Nine patients were treated with interventional reperfusion therapy and the remaining one patient with top of the basilar embolism was treated conservatively because of deep coma and decerebrate rigidity with severely reduced cerebral blood flow ...
H, Ohta, S, Nakano, T, Yano, T, Ohnishi, D, Miyahara, K, Yokogami, T, Goya, S, Wakisaka   +7 more
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Therapy for early reperfusion after stroke

Nature Clinical Practice Cardiovascular Medicine, 2006
Ischemic stroke is a leading cause of death and disability in the Western world. At present, intravenous administration of tissue plasminogen activator within 3 h of symptom onset is the only proven effective treatment to re-establish cerebral blood flow in the case of acute vessel occlusion.
Eric, Juttler, Martin, Kohrmann, Peter D, Schellinger   +2 more
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REPERFUSION THERAPY FOR ACUTE MYOCARDIAL INFARCTION

Emergency Medicine Clinics of North America, 2001
A mechanical approach to reperfusion using direct coronary angioplasty is now an established and effective treatment for acute myocardial infarction, but it is not immediately available at most community hospitals. This article will outline the indications for use of reperfusion therapy on patients with AMI, discuss all currently available treatment ...
J A, McPherson, R S, Gibson
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