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The hydrogen highway to reperfusion therapy

Nature Medicine, 2007
Hydrogen gas debuts as a selective antioxidant with explosive potential as cytoprotective therapy for ischemia-reperfusion injury and stroke.
Katherine C. Wood, Mark T. Gladwin
openaire   +2 more sources

Reperfusion Therapy for Acute Vertebrobasilar Occlusion

Interventional Neuroradiology, 1997
We reviewed retrospectively our experience in treating 10 patients with acute vertebrobasilar occlusion. Nine patients were treated with interventional reperfusion therapy and the remaining one patient with top of the basilar embolism was treated conservatively because of deep coma and decerebrate rigidity with severely reduced cerebral blood flow ...
Ohnishi T   +7 more
openaire   +3 more sources

Management of ‘no‐reflow’ complicating reperfusion therapy

Acute Cardiac Care, 2008
No-reflow phenomenon, defined as inadequate myocardial perfusion of the adequately dilated target vessel without evidence of angiographic mechanical obstruction. It is a multifactorial, well-recognised, secondary phenomenon following reperfusion therapy such as thrombolysis or percutaneous coronary interventions (PCI). The pathophysiological mechanisms
Michael S. Norell, Kaeng W. Lee
openaire   +3 more sources

REPERFUSION THERAPY FOR ACUTE MYOCARDIAL INFARCTION

Emergency Medicine Clinics of North America, 2001
A mechanical approach to reperfusion using direct coronary angioplasty is now an established and effective treatment for acute myocardial infarction, but it is not immediately available at most community hospitals. This article will outline the indications for use of reperfusion therapy on patients with AMI, discuss all currently available treatment ...
Robert S. Gibson, John A. McPherson
openaire   +2 more sources

Microvascular integrity after reperfusion therapy

American Heart Journal, 1999
Several perfusion techniques have definitively shown that microvascular dysfunction plays a crucial role in patients with acute myocardial infarction. In those patients, despite a rapid and sustained restoration of flow throughout a previously occluded epicardial coronary artery, microvascular damage still may be observed.
openaire   +4 more sources

Reperfusion Therapy in Acute Myocardial Infarction

New England Journal of Medicine, 2002
Coronary arterial occlusion due to thrombosis is the cause of most cases of myocardial infarction accompanied by ST-segment elevation.
L. David Hillis, Richard A. Lange
openaire   +3 more sources

Reperfusion Arrhythmias during Coronary Reperfusion Therapy in Man

Chest, 1986
We hypothesized that patients suffering acute myocardial infarction who have reperfusion arrhythmias (RPA) during intracoronary streptokinase infusion (ICSK) would have different clinical and angiographic characteristics and a larger infarction size than those who achieved reperfusion without RPA. Of 35 patients who received intracoronary streptokinase,
Thomas A. Buckingham   +3 more
openaire   +3 more sources

Therapy Against Reperfusion-induced Microvascular Injury

Current Pharmaceutical Design, 2013
No-reflow, i.e., the lack of distal myocardial perfusion to fully recover following recanalization of an acutely occluded coronary artery, is not only a mere consequence of ischemic injury, as substantial microvascular alterations may also develop subsequently, after initial restoration of perfusion.
TRITTO, Isabella   +3 more
openaire   +4 more sources

Reperfusion: Pathophysiologie, Prävention, Therapie

1991
Es ist eine Binsenweiheit, das ohne Reperfusion die Wiederherstellung einer gestorten oder transplantierten Organfunktion nicht moglich ist. Es gibt sogar Untersuchungen, wonach die langfristige Restitution eines zerebralen Insultes um so besser ausfallt, je rigoroser initial reperfundiert wurde [9].
openaire   +2 more sources

Current gaps in acute reperfusion therapies

Current Opinion in Neurology
Purpose of review Advances in intravenous thrombolysis and endovascular thrombectomy have significantly reduced disability and improved outcomes associated with acute ischemic stroke. Recent findings An expansion of indications for reperfusion therapies in select groups of patients ...
Thanh N, Nguyen   +4 more
openaire   +2 more sources

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