Results 81 to 90 of about 4,697,552 (378)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]

open access: yes, 2013
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken   +13 more
core   +3 more sources

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

Study of Antocyanins Activity from Purple Sweet Potato for Reducing Apoptotic Cells Expression of The Cerebellum On Ischemic Stroke Rats [PDF]

open access: yesJournal of Pure and Applied Chemistry Research, 2018
This study aims to determine anthocyanin antioxidant performance with a dose of 2 cc/day based on the expression of apoptotic cells on ischemic stroke rats cerebellum. Research was conducted using ischemic stroke rats (Rattus norvegicus) that prepared by
Made Oka Adnyana   +4 more
doaj   +1 more source

Thrombolysis and thrombectomy for acute ischaemic stroke [PDF]

open access: yes, 2017
The likelihood of disability-free recovery after acute ischemic stroke is significantly improved by reperfusion either by intravenous thrombolytic drug treatment or with endovascular mechanical thrombectomy in selected cases.
El Tawil, Salwa, Muir, Keith W.
core   +1 more source

Reperfusion Adjunctive Therapy: Heparin [PDF]

open access: yesJournal of Interventional Cardiology, 1990
Heparin therapy for patients who have undergone thrombolytic therapy of acute myocardial infarction is logical, and several trials suggest a benefit. However, in the light of the clear adjuvant benefit of aspirin, and the failure of large clinical trials to demonstrate clinically important benefits of heparin, it is not possible to make sound ...
openaire   +1 more source

Melbourne Mobile Stroke Unit and Reperfusion Therapy

open access: yesStroke, 2019
Supplemental Digital Content is available in the text. Background and Purpose— Mobile stroke units (MSUs) are increasingly used worldwide to provide prehospital triage and treatment.
Henry Zhao   +29 more
semanticscholar   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Peculiarities and recommendations of acute stroke treatment during the COVID-19 pandemic

open access: yesNeurologijos seminarai, 2020
The global COVID-19 pandemic poses enormous challenges to healthcare systems and has a major impact on the treatment and care of stroke patients. In the article, the authors review the issues of acute stroke diagnosis, treatment, and prevention during ...
A. Vilionskis   +3 more
doaj   +1 more source

Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy [PDF]

open access: yes, 2010
Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Babu, Suresh   +2 more
core   +1 more source

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