Results 81 to 90 of about 4,697,552 (378)
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken+13 more
core +3 more sources
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
Study of Antocyanins Activity from Purple Sweet Potato for Reducing Apoptotic Cells Expression of The Cerebellum On Ischemic Stroke Rats [PDF]
This study aims to determine anthocyanin antioxidant performance with a dose of 2 cc/day based on the expression of apoptotic cells on ischemic stroke rats cerebellum. Research was conducted using ischemic stroke rats (Rattus norvegicus) that prepared by
Made Oka Adnyana+4 more
doaj +1 more source
Thrombolysis and thrombectomy for acute ischaemic stroke [PDF]
The likelihood of disability-free recovery after acute ischemic stroke is significantly improved by reperfusion either by intravenous thrombolytic drug treatment or with endovascular mechanical thrombectomy in selected cases.
El Tawil, Salwa, Muir, Keith W.
core +1 more source
Reperfusion Adjunctive Therapy: Heparin [PDF]
Heparin therapy for patients who have undergone thrombolytic therapy of acute myocardial infarction is logical, and several trials suggest a benefit. However, in the light of the clear adjuvant benefit of aspirin, and the failure of large clinical trials to demonstrate clinically important benefits of heparin, it is not possible to make sound ...
openaire +1 more source
Melbourne Mobile Stroke Unit and Reperfusion Therapy
Supplemental Digital Content is available in the text. Background and Purpose— Mobile stroke units (MSUs) are increasingly used worldwide to provide prehospital triage and treatment.
Henry Zhao+29 more
semanticscholar +1 more source
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im+10 more
wiley +1 more source
Peculiarities and recommendations of acute stroke treatment during the COVID-19 pandemic
The global COVID-19 pandemic poses enormous challenges to healthcare systems and has a major impact on the treatment and care of stroke patients. In the article, the authors review the issues of acute stroke diagnosis, treatment, and prevention during ...
A. Vilionskis +3 more
doaj +1 more source
Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy [PDF]
Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Babu, Suresh+2 more
core +1 more source