Results 191 to 200 of about 889,250 (400)

Editorial: Immune system modeling and analysis

Frontiers in Immunology, 2014
Ramit eMehr
doaj   +1 more source

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

, 2012
Bryan Briney, Jordan R. Willis, Mark D. Hicar, James W. Thomas, James E. Crowe   +4 more
openalex   +2 more sources

An inference model gives insights into innate immune adaptation and repertoire diversity [PDF]

, 2023
Yawei Qin, Emily M. Mace, John P. Barton
openalex   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

The substrate repertoire of γ-secretase/presenilin.

Seminars in Cell and Developmental Biology, 2020
Gökhan Güner, S. Lichtenthaler
semanticscholar   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

T cell receptor repertoire in mucosal lymphocytes of patients with inflammatory bowel disease

, 1994
Takuya Matsumoto, W.R. Brown, Atsuo Kitano, Keita Adachi, Shinichiro Nakamura, Yasuhiro Watanabe, T. Aoki, A. Obata, N. Oshitani, Thomas Prindiville, Mary C. Cantrell, E. Gershwin, Brian L. Kotzin   +12 more
openalex   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Author response: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

, 2019
Rebeca Jimeno, Marta Lebrusant‐Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gavin Kelly, Gurdyal S. Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral   +10 more
openalex   +1 more source