Results 61 to 70 of about 10,081 (245)

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Utilising the repertory grid technique in visual prosthetic design : promoting a user-centred approach [PDF]

open access: yes, 2016
This paper proposes a new User-Centred data-collection methodology based on the 9 Repertory Grid Technique (RGT) for the aesthetic design of below-knee prostheses.
Buis, Arjan   +3 more
core   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

open access: yesAdvanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Exploring Users’ Mental Models for Anthropomorphized Voice Assistants through Psychological Approaches

open access: yesApplied Sciences, 2021
Various perspectives are being studied to increase the usability and persistence of voice assistants (VA) as the use is rapidly expanding to various domains. Particularly, many studies note that users personify VA.
Dasom Park, Kiechan Namkung
doaj   +1 more source

Measuring brand image: Shopping centre case studies [PDF]

open access: yes, 2002
'Branding' is well known for consumer products but power has shifted from manufacturers' brands towards retailers'. The term 'image' is more common than 'brand' in the context of shopping centres, but 'branding' may become more important.
Cockett, T   +4 more
core   +1 more source

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto   +3 more
wiley   +1 more source

Exploring consumer product construct systems with the repertory grid technique

open access: yesQualitative Market Research: An International Journal, 2000
Examines some of the applications of repertory grid technique and theory to qualitative market research. In particular, it shows how together they can be used to explore five basic components of the network of subjective meanings that consumers attach to their consumption experiences, what are termed here consumers’ product construct systems (PCSs ...
Marsden, D., Littler, Dale
openaire   +2 more sources

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

open access: yesiMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui   +9 more
wiley   +1 more source

Balancing dual roles in self-employed women: An exploratory study

open access: yesSA Journal of Industrial Psychology, 2009
This study is aimed at exploring how self-employed women cope in balancing their dual roles as mothers and executives. Through the elicitation of constructs by making use of Kelly’s repertory grid technique, the personal construct system of five self ...
Kirsty-Lee McLellan, Koos Uys
doaj   +1 more source

Double-loop reflective practice as an approach to understanding knowledge and experience. [PDF]

open access: yes, 2016
The main aim of this paper is to consider the way in which reflective practice can assist practitioners in better understanding their individual knowledge and experience.
Aftab, Mersha   +3 more
core   +1 more source

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