Results 111 to 120 of about 1,683,548 (326)

DIDACTIC PERSPIRATION IN SHANGHAI: EXPLANATORY THEORIES UNDERLYING A MODEL OF BEST PRACTICES [PDF]

open access: yesAnalele Universităţii din Craiova. Psihologie, Pedagogie
Students in Shanghai, China, achieved the highest global scores in mathematics, science, and reading comprehension in the 2012 PISA assessment, outperforming education systems around the world.
Jean Désiré BANGA AMVÉNÉ
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Derandomized Parallel Repetition via Structured PCPs [PDF]

open access: yes, 2014
A PCP is a proof system for NP in which the proof can be checked by a probabilistic verifier. The verifier is only allowed to read a very small portion of the proof, and in return is allowed to err with some bounded probability.
Dinur, Irit, Meir, Or
core   +1 more source

Heat accumulation effects in femtosecond laser-written waveguides with variable repetition rate.

open access: yesOptics Express, 2005
High-repetition rate femtosecond lasers are shown to drive heat accumulation processes that are attractive for rapid writing of low-loss optical waveguides in transparent glasses.
S. Eaton   +6 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Generation of optical frequency combs with a CaF2 resonator [PDF]

open access: yes, 2009
We demonstrate optical frequency combs using the fluorite whispering gallery mode resonator as a nonlinear Kerr medium. Two regimes of generation are observed, giving the record low repetition rate of 13 GHz, equal to the cavity's free spectral range ...
Grudinin, Ivan S., Maleki, Lute, Yu, Nan
core  

Risk Factors for Repetition of Self-Harm: A Systematic Review of Prospective Hospital-Based Studies

open access: yesPLoS ONE, 2014
Background Self-harm entails high costs to individuals and society in terms of suicide risk, morbidity and healthcare expenditure. Repetition of self-harm confers yet higher risk of suicide and risk assessment of self-harm patients forms a key component ...
C. Larkin, Z. Di Blasi, E. Arensman
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Szymborska, Read from the End

open access: yesPoznańskie Studia Polonistyczne. Seria Literacka, 2013
The essay is about Wisława Szymborska’s late poetry, especially the last volume, Wystarczy [Enough]. The poet’s frequent returns, repetitions, and various references to her earlier work are of particular importance.
Janina Abramowska
doaj   +1 more source

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