Results 131 to 140 of about 819,894 (311)
, 1994 This thesis will concern control systems ability to enhance performance by repeating, while maintaining a stable and sufficiently fast closed loop performance. Iterative techniques can be divided into repetitive and learning control. In principle these techniques only differ in that the learning systems initial condition is reset at the beginning of ...
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Active disturbance rejection repetitive control method for dual Buck converter in microgrid
Diance yu yibiaoIn microgrid, the presence of multiple renewable energy sources as power supplies, coupled with the influence of complex operating conditions, makes it challenging to ensure the output power quality.
LI Jiwei +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On the Control of Distributed Parameter Systems using a Multidimensional Systems Setting
, 2008 The unique characteristic of a repetitive process is a series of sweeps, termed passes, through a set of dynamics defined over a finite duration with resetting before the start of the each new one.
Augusta, P +4 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Scheduling of non-repetitive lean manufacturing systems under uncertainty using intelligent agent simulation [PDF]
, 2008 World-class manufacturing paradigms emerge from specific types of manufacturing systems with which they remain associated until they are obsolete. Since its introduction the lean paradigm is almost exclusively implemented in repetitive manufacturing ...
Mousavi, A, Papadopoulou, T C
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
IEEE Open Journal of Industry ApplicationsRepetitive controller provides a very low third harmonic dimension in the quantities under control. It exhibits an inherent issue when operated to track variable frequency references.
Alessandro Faro +4 more
doaj +1 more source