Results 181 to 190 of about 71,813 (221)

Intra-strain genetic heterogeneity in Toxoplasma gondii ME49: Oxford Nanopore long-read sequencing reveals copy number variation in the ROP8-ROP2A locus. [PDF]

BMC Genomics
Gohar Y, Neumann M, Hülse L, Wind D, Mock J, Buchholz K, Helle M, Sorg UR, Degrandi D, Pfeffer K, Dilthey A.   +10 more
europepmc   +1 more source

Thermodynamic Determinants in Antibody-Free Nucleic Acid Lateral Flow Assays (AF-NALFA): Lessons from Molecular Detection of <i>Listeria monocytogenes</i>, <i>Mycobacterium leprae</i> and <i>Leishmania amazonensis</i>. [PDF]

Biomolecules
Lopes-Luz L, Neddermeyer PC, Sampaio GC, Alves LM, Fogaça MBT, Saavedra DP, Stefani MMA, Bührer-Sékula S.   +7 more
europepmc   +1 more source

Visualization and quantification of rDNA instabilities in mammalian cells and mouse models. [PDF]

Nucleic Acids Res
Zhu X, Jiang W, Wu W, Lee BJ, Menolfi D, Tubbs A, Cupo OM, Malkovskiy E, Nester M, Wang XS, Sims PA, Lin CV, Symington L, Nussenzweig A, McStay B, Zha S.   +15 more
europepmc   +1 more source

Repeats mimic pathogen-associated patterns across a vast evolutionary landscape. [PDF]

Cell Genom
Šulc P, Di Gioacchino A, Solovyov A, Sun S, Martis S, Marhon SA, Lindholm HT, Chen R, Hosseini A, Jiang H, Ly BH, Taylor MS, Mehdipour P, Abdel-Wahab O, Rusk N, Vabret N, LaCava J, De Carvalho DD, Monasson R, Cocco S, Greenbaum BD.   +20 more
europepmc   +1 more source

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Time and Memory Efficient Algorithm for Extracting Palindromic and Repetitive Subsequences in Nucleic Acid Sequences

Biocomputing '99, 1998
Genomic science and structural biology meet in the relationship between the sequence and the structure of nucleic acids. The structure that supports each function is preserved in the process of evolution as specific sequences. Particularly, the same sequence which appears in a different place such as a palindromic or repetitive sequence has biophysical
T, Tsunoda, M, Fukagawa, T, Takagi
openaire   +3 more sources

Development of a Colorimetric and SERS Dual-Signal Platform via dCas9-Mediated Chain Assembly of Bifunctional Au@Pt Nanozymes for Ultrasensitive and Robust Salmonella Assay.

Analytical Chemistry
Timely screening for harmful pathogens is a great challenge in emergencies where traditional culture methods suffer from long assay time and alternative methods are limited by poor accuracy and low robustness.
Han Jiang, W. Chang, Xiaofan Zhu, Gang Liu, Kaiyong Liu, Wei Chen, Hua Wang, Panzhu Qin   +7 more
semanticscholar   +1 more source

Synchronous Dual-Cycle Amplification System Based on Programmable Ago-DNA Polymerase for Detecting Tumor-Related MicroRNAs.

Analytical Chemistry
Detecting nucleic acid biomarkers is essential for early cancer diagnosis and monitoring. Traditional methods (e.g., exponential isothermal amplification (EXPAR)) adopt DNA polymerases and endonucleases for nucleic acid amplification and analysis, but ...
Qiuyuan Lin, Yicheng Huang, Junchao Chen, Zhenxin Lei, Mingwei Yang, Mierhaitireye Kudouluke, Guangjian Su, Jinghua Chen   +7 more
semanticscholar   +1 more source

Multiple RNA Rapid In Situ Imaging Based on Cas9 Code Key System

Small Methods
Existing RNA in situ imaging strategies mostly utilize parallel repetitive nucleic acid self‐assembly to achieve multiple analysis, with limitations of complicated systems and cumbersome steps. Here, a Cas9 code key system with key probe (KP) encoder and
Ruiwei Hu, Wei Yang, Jia Li, Lanxin Jiang, Menghan Li, Mengxuan Zhang, Yuexi Kang, Xiaoxue Cheng, Shasha Zhu, Lina Zhao, Wen He, Minghui Guo, Shijia Ding, Haiping Wu, W. Cheng   +14 more
semanticscholar   +1 more source