Results 61 to 70 of about 82,762 (234)

DNA‐Origami‐Assembled Rhodium Nanoantennas for Deep‐UV Label‐Free Single‐Protein Detection

Advanced Functional Materials, EarlyView.
Deep‐UV autofluorescence of single proteins in DNA origami‐based rhodium nanoantennas. Precisely positioned within the plasmonic nanogap, proteins retain their native state while their intrinsic emission is strongly amplified, enabling label‐free single‐molecule detection and opening new opportunities for highly sensitive and specific biosensing ...
Nicco Corduri, Malavika Kayyil Veedu, Yifan Yu, Yanqiu Zou, Jie Liu, Denis Garoli, Guillermo P. Acuna, Jérôme Wenger, Karol Kołątaj   +8 more
wiley   +1 more source

Ribosome signatures aid bacterial translation initiation site identification [PDF]

, 2017
Background: While methods for annotation of genes are increasingly reliable, the exact identification of translation initiation sites remains a challenging problem.
Chyżyńska, Katarzyna, Giess, Adam, Jonckheere, Veronique, Ndah, Elvis, Valen, Eivind, Van Damme, Petra   +5 more
core   +2 more sources

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Capillary electrophoresis fragment analysis and clone sequencing in detection of dynamic mutations of spinocerebellar ataxia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To estimate the accuracy and stability of capillary electrophoresis fragment analysis and clone sequencing in detecting dynamic mutations of spinocerebellar ataxia (SCA). Methods Capillary electrophoresis fragment analysis and clone sequencing
Yuan-yuan CHEN, Ying HAO, Jin ZHANG, Xin ZHANG, Kun-ming XIE, Ming DING, Wei-hong GU   +6 more
doaj  

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]

, 1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask, C Cremer, D Pinkel, D Pinkel, D. C. Ward, DA Agard, DJ Brigati, DJ Finney, GA Rappold, GD Johnson, GJ Brakenhoff, H Hamada, HE McDermid, HJ Cooke, J. Borden, JE Landegent, JG White, JR Gosden, JS Waye, L Hens, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, L. Manuelidis, LG Davis, M Schardin, MA Dilla Van, ML Mendelsohn, P. Lichter, PG Sealey, PR Langer, RJ Britten, T Cremer, T Cremer, T Cremer, T Cremer, T Maniatis, T. Cremer   +39 more
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Mutual information for examining correlations in DNA

, 2004
This paper examines two methods for finding whether long-range correlations exist in DNA: a fractal measure and a mutual information technique. We evaluate the performance and implications of these methods in detail.
A. ALLISON, D. ABBOTT, Dover G. A., Joset F., M. J. BERRYMAN   +4 more
core   +2 more sources

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages [PDF]

, 2012
There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease.
A Deshpande, AC Schürch, AC Schürch, AG Tsolaki, BC de Jong, BC de Jong, Bijaya Malla, C Allix-Béguec, C Bouakaze, C Bouakaze, C Demay, CM Sassetti, CM Sassetti, CRE McEvoy, D Portevin, D Yeboah-Manu, DA Milner Jr, David Stucki, Dorothy Yeboah-Manu, E Abadia, ES Click, G Thwaites, H Yesilkaya, I Comas, I Comas, I Filliol, I Filliol, I Parwati, Igor Mokrousov, IL Bergval, Iñaki Comas, J Kamerbeek, J Song, J Zhi, J Zhi, JD van Embden, JP Schouten, Julia Feldmann, K Okonechnikov, K Tamura, L Baker, L Fenner, L Fenner, L Flores, L Kaderali, L Wang, LE Espinosa de los Monteros, LS Cowan, Lukas Fenner, M Ben Shabat, M Caws, M Caws, M Coscolla, M Kato-Maeda, M Kato-Maeda, Mireia Coscollà, MM Gutacker, MP Nicol, NH Smith, O Mestre, P Keim, P Supply, P Supply, PM Groenen, PM Holland, PM Vallone, R Hershberg, S Gagneux, S Homolka, S Kim, S Sreevatsan, S-H Lee, SA Dunbar, SD Bentley, Sebastien Gagneux, Simon Hostettler, Sonia Borrell, ST Cole, T Pearson, TA Halse, Thembela Huna, U Nübel, WP Maddison   +82 more
core   +4 more sources

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source