Identification of novel regulatory elements in sequenced genomes by clustering and other data mining methods [PDF]
, 2009 In bacterial genomes a fraction of transcribed sequences do not code for proteins or structural RNAs, but have been shown to be involved in fundamental processes, such as regulation of gene expression, mRNA processing and stability or structural RNA ...
Cozzuto, Luca
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RIPCAL: a tool for alignment-based analysis of repeat-induced point mutations in fungal genomic sequences [PDF]
, 2008 Background Repeat-induced point mutation (RIP) is a fungal-specific genome defence mechanism that alters the sequences of repetitive DNA, thereby inactivating coding genes.
Hane, J. +7 more
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Repeated sequences in linear genetic programming genomes [PDF]
, 2005 Biological chromosomes are replete with repetitive sequences, micro satellites, SSR tracts, ALU, etc. in their DNA base sequences. We started looking for similar phenomena in evolutionary computation.
Banzhaf, W., Langdon, W.B.
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Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]
, 2011 Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Christina Troiber +3 more
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Nucleic Acid (Patent US 2009/0019559 A1) [PDF]
, 2009 The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a Delta8-desaturase and a Delta5-desaturase enzyme.
Sayanova, O. V. +2 more
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Nucleic Acid (Patent WO 2007/093776 A2) [PDF]
, 2007 The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a ?8-desaturase and a ?5-desaturase enzyme.
Sayanova, O. V. +2 more
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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]
, 2003 Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Tan, T. H. Samuel +14 more
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Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
, 2020 In nature, genomes have been optimized by the evolution of their nucleic acid sequences. The design of peptide-like carriers as synthetic sequences provides a strategy for optimizing multifunctional targeted nucleic acid delivery in an iterative process.
Yanfang Wang, Ernst Wagner
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Prebiotically Plausible Mechanisms Increase Compositional Diversity Of Nucleic Acid Sequences [PDF]
, 2012 During the origin of life, the biological information of nucleic acid polymers must have increased to encode functional molecules (the RNA world). Ribozymes tend to be compositionally unbiased, as is the vast majority of possible sequence space. However,
Manapat, Michael +20 more
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Repetitive flanking sequences (ReFS): novel molecular markers from microsatellite families
, 2007 Although microsatellite markers have become exceedingly popular in molecular studies of wild organisms, their development in some taxonomic groups is challenging.
Gould, P. +6 more
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