Results 21 to 30 of about 3,743,423 (243)

Molecular cytogenetic mapping of Cucumis sativus and C. melo using highly repetitive DNA sequences [PDF]

, 2010
Chromosomes often serve as one of the most important molecular aspects of studying the evolution of species. Indeed, most of the crucial mutations that led to differentiation of species during the evolution have occurred at the chromosomal level ...
Jong, J.H.S.G.M., de, Choi, D., Koo, D.H., Hur, Y., Bang, J.W., Nam, Y.W.   +5 more
core   +1 more source

RPiRLS: Quantitative Predictions of RNA Interacting with Any Protein of Known Sequence

Molecules, 2018
RNA-protein interactions (RPIs) have critical roles in numerous fundamental biological processes, such as post-transcriptional gene regulation, viral assembly, cellular defence and protein synthesis.
Wen-Jun Shen, Wenjuan Cui, Danze Chen, Jieming Zhang, Jianzhen Xu   +4 more
doaj   +1 more source

Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole

Scientific Reports, 2017
G-quadruplex (G4) is a higher-order nucleic acid structure that is formed by guanine-rich sequences. G4 stabilization by small-molecule compounds called G4 ligands often causes cytotoxicity, although the potential medicinal impact of this effect has not ...
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa, Hiroyuki Seimiya   +10 more
doaj   +1 more source

Optimized Lysis-Extraction Method Combined With IS6110-Amplification for Detection of Mycobacterium tuberculosis in Paucibacillary Sputum Specimens

Frontiers in Microbiology, 2018
Background: When available, nucleic acid tests (NATs) offer powerful tools to strengthen the potential of tuberculosis (TB) diagnosis assays. The sensitivity of molecular assays is critical for detection of Mycobacterium tuberculosis (MTB) in ...
Pratt Kolia-Diafouka, Sylvain Godreuil, Arnaud Bourdin, Severine Carrère-Kremer, Laurent Kremer, Philippe Van de Perre, Edouard Tuaillon   +6 more
doaj   +1 more source

Nucleic acid and amino acid sequences of ZjOMTPosition.

, 2018
Nucleic acid and amino acid sequences of ZjOMTPosition.
Hongsong Luo (5180807), Liebao Han (2579935), Chunyan He (149909)   +2 more
core   +1 more source

Means and methods for cloning nucleic acid sequences [PDF]

, 2008
The invention provides means and methods for efficiently cloning nucleic acid sequences of interest in micro-organisms that are less amenable to conventional nucleic acid manipulations, as compared to, for instance, E.coli.
Geertsma, Eric Robin, Poolman, Berend
core   +4 more sources

Nucleic acid sequences for miRNAs and siRNA mimics.

, 2013
Nucleic acid sequences for miRNAs and siRNA mimics.
Yaou Zhang (63065), Naihan Xu (389220), Qing Lv (63057), Jie He (132999), Weidong Xie (344815), Nunu Huang (389221), Mengnan Li (389219)   +6 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Nucleic Acid (Patent US 2009/0019559 A1) [PDF]

, 2009
The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a Delta8-desaturase and a Delta5-desaturase enzyme.
Sayanova, O. V., Caleron, M. V., Napier, J. A.   +2 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source