Results 1 to 10 of about 3,522,596 (141)

Clinical and genetic study of a juvenile⁃onset Huntington disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Background Huntington's disease (HD) is an autosomal dominant hereditary progressive neurodegenerative disorder with a distinct phenotype characterized by chorea, dementia, cognitive and affective impairment.
Ying HAO, Yuan⁃yuan CHEN, Wei⁃hong GU, Guo⁃xiang WANG, Hui⁃zi MA, Li⁃lin LI, Kang WANG, Miao JIN, Xiao⁃hui DUAN   +8 more
doaj  

Capillary electrophoresis fragment analysis and clone sequencing in detection of dynamic mutations of spinocerebellar ataxia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To estimate the accuracy and stability of capillary electrophoresis fragment analysis and clone sequencing in detecting dynamic mutations of spinocerebellar ataxia (SCA). Methods Capillary electrophoresis fragment analysis and clone sequencing
Yuan-yuan CHEN, Ying HAO, Jin ZHANG, Xin ZHANG, Kun-ming XIE, Ming DING, Wei-hong GU   +6 more
doaj  

Complete chloroplast genomes and phylogenetic relationships of Pedicularis chinensis and Pedicularis kansuensis

Scientific Reports
The complete cp genomes of Pedicularis chinensis (GenBank accession number: OQ587614) and Pedicularis kansuensis (GenBank accession number: OQ587613) were sequenced, assembled, and annotated. Their chloroplast (cp) genome lengths were 146,452 bp, and 146,
Tao Wang, Xiuzhang Li, Chuyu Tang, Zhengfei Cao, Hui He, Xiaoping Ma, Yuling Li, Kejia De   +7 more
doaj   +1 more source

A comprehensive study of Z-DNA density and its evolutionary implications in birds

BMC Genomics
Background Z-DNA, a left-handed helical form of DNA, plays a significant role in genomic stability and gene regulation. Its formation, associated with high GC content and repetitive sequences, is linked to genomic instability, potentially leading to ...
Yu-Ren Wang, Shao-Ming Chang, Jinn-Jy Lin, Hsiao-Chian Chen, Lo-Tung Lee, Dien-Yu Tsai, Shih-Da Lee, Chung-Yu Lan, Chuang-Rung Chang, Chih-Feng Chen, Chen Siang Ng   +10 more
doaj   +1 more source

Applications and development of in situ nucleic acid visualization techniques. [PDF]

Front Bioeng Biotechnol
Chen S, Wei D.
europepmc   +1 more source

Alternative nucleic acid structures in microbial biology: regulatory functions and antimicrobial opportunities. [PDF]

Front Cell Infect Microbiol
Yousuf S, M M, Bhat S.
europepmc   +1 more source

Short Tandem Repeat 3D Structure Database (STR3SD): A Resource for Structural Biology Research of Short Tandem Repeats in Neurodegenerative Disorders. [PDF]

Int J Mol Sci
Jie K, Song A, Wang Y, Liu Y, Liu Y, Guo M, Zhang Z, Xu N, Tao Y, Wan L, Qiu J, Guo P.   +11 more
europepmc   +1 more source

Decoding sequence recognition code of nucleic acid-binding proteins of human-infecting DNA viruses. [PDF]

Imeta
Tang M, Yang S, Ma H, Guo R, Chen J, Zhang H, Zhang J, Sun W, Wei Y, Fan L, Yan J.   +10 more
europepmc   +1 more source

ZBP1 in Neuroinflammation and Neurodegeneration: Z-Nucleic-Acid Sensing, RHIM Signalling and Therapeutic Targeting. [PDF]

Int J Mol Sci
Șerban M, Toader C, Covache-Busuioc RA.
europepmc   +1 more source

Protein-directed nucleotide selection in the DRT3 defense system: mechanism, biological context, and constraints on programmability. [PDF]

Front Microbiol
Niazi SK.
europepmc   +1 more source