Results 11 to 20 of about 3,743,423 (243)

METHOD FOR INDEXING NUCLEIC ACID SEQUENCES FOR COMPUTER BASED SEARCHING [PDF]

, 2023
The present invention relates to a method for indexing nucleic acid sequences to aid computer based searching of nucleic acid sequences by indexing a nucleotide sequence by the presence of unique Kmers in the sequence. The method of the present invention

core   +2 more sources

Algorithms for Nucleic Acid Sequence Design [PDF]

, 2010
Motivated by a growing field of research focused on programming function into biomolecules, we seek to decrease the cost of high-quality rational nucleic acid sequence design while increasing its versatility and availability.
Zadeh, Joseph N.
core   +1 more source

STR technique for the detection of contamination by exogenous DNA in paraffin blocks and histological slides

Surgical and Experimental Pathology, 2019
Gastrointestinal Stromal Tumors (GIST) present different types of mutations that may or may not be sensitive to specific target therapy. The laboratory procedure required to prepare histological sections traditionally demands multiple steps, making the ...
Denise Barcelos, Karina Funabashi, Susana Mazloum, Mariana Fernandes, Leonardo Cardili   +4 more
doaj   +1 more source

Rapid capture of DNA targets

BioTechniques, 2008
A rapid capture technique was developed to efficiently isolate specific DNA targets from a variety of genomes. The specificity can be easily adapted to any target for which partial sequence is known, allowing for the isolation of a wide set of target ...
Judy St. John, Thomas W. Quinn
doaj   +1 more source

Analysis of a c0t-1 library enables the targeted identification of minisatellite and satellite families in Beta vulgaris [PDF]

, 2010
Zakrzewski F, Wenke T, Holtgräwe D, Weisshaar B, Schmidt T. Analysis of a c0t-1 library enables the targeted identification of minisatellite and satellite families in Beta vulgaris. BMC Plant Biology.
Zakrzewski, Falk, Wenke, Torsten, Zakrzewski Falk, Falk Zakrzewski, Bernd Weisshaar, Weisshaar Bernd, Thomas Schmidt, Weisshaar, Bernd ; https://orcid.org/, Schmidt Thomas, Torsten Wenke, Daniela Holtgräwe, Wenke Torsten, Holtgräwe Daniela, Holtgräwe, Daniela ; https://orcid.org/, Schmidt, Thomas   +14 more
core   +1 more source

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Multiple sequence alignments of partially coding nucleic acid sequences [PDF]

, 2018
High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, however, exhibit a much larger sequence heterogeneity compared to their encoded protein
Hofacker, Ivo L., Fried, Claudia, Stadler, Peter F., Stocsits, Roman R.   +3 more
core   +2 more sources

General cell-binding activity of intramolecular G-quadruplexes with parallel structure.

PLoS ONE, 2013
G-quadruplexes (G4s) are four-stranded nucleic acid structures adopted by some repetitive guanine-rich sequences. Putative G-quadruplex-forming sequences (PQSs) are highly prevalent in human genome.
Tianjun Chang, Cui Qi, Jie Meng, Nan Zhang, Tao Bing, Xianda Yang, Zehui Cao, Dihua Shangguan   +7 more
doaj   +1 more source

Systematic identification of stem-loop containing sequence families in bacterial genomes

BMC Genomics, 2008
Background Analysis of non-coding sequences in several bacterial genomes brought to the identification of families of repeated sequences, able to fold as secondary structures.
Silvestro Giustina, Petrillo Mauro, Cozzuto Luca, Di Nocera Pier, Paolella Giovanni   +4 more
doaj   +1 more source

Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells

Frontiers in Pharmacology, 2020
The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome.
Gabriela Zavala, Gabriela Zavala, María-Paz Ramos, María-Paz Ramos, Aliosha I. Figueroa-Valdés, Aliosha I. Figueroa-Valdés, Pablo Cisternas, Ursula Wyneken, Macarena Hernández, Macarena Hernández, Pauline Toa, Brian Salmons, John Dangerfield, Walter H. Gunzburg, Maroun Khoury, Maroun Khoury, Maroun Khoury   +16 more
doaj   +1 more source