Results 91 to 100 of about 3,382,502 (337)

Token replacement-based data augmentation methods for hate speech detection [PDF]

, 2022
Kosisochukwu Judith Madukwe, Xiaoying Gao, Bing Xue   +2 more
openalex   +1 more source

The effects of replacement schemes on car sales: the Spanish case [PDF]

This paper studies a model of car replacement designed to evaluate policies addressed to influence replacement decisions. An aggregate hazard function is computed from optimal replacement rules of heterogeneous consumers, which mimics the hump-shaped ...
Antonio R. Sampayo, Omar Licandro
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Peritonitis-induced peritoneal injury models for research in peritoneal dialysis review of infectious and non-infectious models

Renal Replacement Therapy, 2017
Peritonitis is an important complication of peritoneal dialysis. Several animal peritonitis models have been described, including bacterial and fungal models that are useful for studying inflammation in peritonitis. However, these models have limitations
Yasuhiko Ito, Hiroshi Kinashi, Takayuki Katsuno, Yasuhiro Suzuki, Masashi Mizuno   +4 more
doaj   +1 more source

The rotational position of the aortic valve: implications for valve-sparing aortic root replacement [PDF]

, 2022
Kiyotoshi Oishi, Hirokuni Arai, Keiji Oi, Eiki Nagaoka, Masafumi Yashima, Tatsuki Fujiwara, Masashi Takeshita, Tomohiro Mizuno   +7 more
openalex   +1 more source

Replacing factor VIII replacement? [PDF]

Science, 2016
Medicine Hemophilia A is a bleeding disorder caused by a deficiency of factor VIII, a protein essential for blood clotting. Injection of recombinant or plasma-derived factor VIII is an effective prophylactic treatment. Factor replacement therapy has drawbacks, however, as it requires multiple injections each week and can induce antibodies that inhibit ...
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Role and Results of Constrained Insert in Computer-Assisted Primary Total Knee Arthroplasty: A Propensity-Matched Study

Arthroplasty Today
Purpose: Mild ligament imbalance is often encountered in the mediolateral plane during complex primary total knee arthroplasty. A constrained (CP) polyethylene insert compatible with the primary femur is useful to manage these cases without the need to ...
Anoop Jhurani, MS, Piyush Agarwal, MS, Hardik Sahni, MS, Gaurav Ardawatia, MS, Mudit Srivastava, MSc   +4 more
doaj   +1 more source

Computer navigation has no beneficial effect on blood loss and transfusion in sequential bilateral total knee Arthroplasty

Journal of Orthopaedic Surgery, 2019
Background: Bilateral total knee arthroplasty is associated with significant blood loss. Postoperative anaemia retards patients recovery, and blood transfusion increases the risk for major complications including infection.
Anoop Jhurani, Piyush Agarwal, Mukesh Aswal, Pramod Jain, Sricharan Malepati, Ritu Sharma   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source