Results 101 to 110 of about 3,207,924 (350)

Rapid reduction in surgical time and high level of accuracy in alignment and femoral component size prediction in robotic‐assisted total knee arthroplasty with ROSA Knee System

open access: yesJournal of Experimental Orthopaedics
Purpose Robotic‐assisted total knee arthroplasty (RA‐TKA) has gained popularity for its potential ability to improve surgical precision and patient outcomes, despite concerns about its long learning curve and increased operative times.
Stefano Petrillo   +3 more
doaj   +1 more source

Inventory management in railway sleepers: A simulation model for replacement strategies [PDF]

open access: yes, 2000
This paper describes the development of a simulation model to assess the inventory requirements of alternative rail sleeper replacement strategies. The main aim of the model is to determine the optimal replacement strategy, given replacement costs and ...
Ferreira, Luis, Yun, Won Young
core   +1 more source

To Replace or Not to Replace: Determining Optimal Replacement Rates in Beef Cattle Operations

open access: yesThe Professional Animal Scientist, 2004
Data from a Nebraska cattle ranch were used to compare three female replacement strategies to determine optimal replacement and marketing strategies of females for maximizing the long-term profit potential of that operation. The income statement model (ISM) maximized 10-yr net income by altering the number of females marketed from different age ...
Mackay, W. S.   +5 more
openaire   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Antenna grout replacement system [PDF]

open access: yes, 1983
An epoxy grout suitable for use in mounting and positioning bearing runner plates used in hydrostatic bearing assemblies for rotatably mounting large radio telescope structures to stationary support pedestals is described.
Mcclung, C. E.
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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