Results 281 to 290 of about 1,930,945 (365)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

open access: yesAdvanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso   +5 more
wiley   +1 more source

Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture

open access: yesAdvanced Engineering Materials, EarlyView.
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee   +3 more
wiley   +1 more source

Soft‐Layered Composites with Wrinkling‐Activated Multi‐Linear Elastic Behavior, Stress Mitigation, and Enhanced Strain Energy Storage

open access: yesAdvanced Engineering Materials, EarlyView.
In this study, exciting new bi‐/multi‐linear elastic behavior of soft elastic composites that accompany the activation of wrinkling in the embedded interfacial layers is analyzed. The new features and performance of these composite materials, including dramatic enhancements in energy storage, can be tailored by the concentration of interfacial layers ...
Narges Kaynia   +2 more
wiley   +1 more source

Economic Impact of Abortions in Dairy Cow Herds. [PDF]

open access: yesVet Sci
Palma O   +3 more
europepmc   +1 more source

A Case‐Based Reasoning Approach to Model Manufacturing Constraints for Impact Extrusion

open access: yesAdvanced Engineering Materials, EarlyView.
A hybrid modeling approach is presented that combines constraint‐based process modeling and case‐based reasoning. The model formalizes manufacturing constraints and integrates simulation data to model complex manufacturing processes. The approach supports manufacturability analysis during product design through an adaptive modeling environment.
Kevin Herrmann   +5 more
wiley   +1 more source

Assessing the Ecological Value: Monetizing Process Innovations in Tailored Forming

open access: yesAdvanced Engineering Materials, EarlyView.
This article introduces a method for evaluating the sustainability of innovations, even with limited data. The method is illustrated through an analysis of the “Tailored Forming” technology, which explores the impact of sustainability on economic value added.
Jonas Schneider   +4 more
wiley   +1 more source

A case of hypopituitarism with pancytopenia cured by corticosteroid and thyroid hormone replacement therapy. [PDF]

open access: yesEndocrinol Diabetes Metab Case Rep
Mladenovic V   +7 more
europepmc   +1 more source

Mechanisms of Increasing Weld Depth during Temporal Power Modulation in High‐Power Laser Beam Welding

open access: yesAdvanced Engineering Materials, EarlyView.
Temporal power modulation increases weld depth in high‐power laser beam welding of dissimilar round bars by nearly 20% compared to same average continuously welded welding power. The mechanism of action also applies to sheet welding and depends on the inertia of keyhole depth for the modulated laser beam power.
Jan Grajczak   +7 more
wiley   +1 more source

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