Results 151 to 160 of about 868,934 (253)

Prevalence of Infectious Pathogens Among Voluntary and Replacement Blood Donors in Pakistan: An 18-Year Experience. [PDF]

Cureus
Ahmad N, Asif H, Sultan F, Nizamuddin S, Mahmood MT, Ahmad AH, Ching C, Zaman MH.   +7 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Utilization and outcomes of organs from ECMO-supported brain-dead donors: two-center experience. [PDF]

J Intensive Care
Chung J, Ko RE, Cha S, Oh S, Lim SK, Yang JH, Sung K, Ju MH, Cho YH.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Incidence of <i>Treponema pallidum</i> in donors from a blood centre in Colombia, 2012-2024. [PDF]

Epidemiol Infect
González-Tamayo L, Saldarriaga-Vélez S, Villa-Carrasquilla J, Gil-Betancur A, Cardona-Arias JA.   +4 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Culturing neutrophils from human CD34⁺ HSPCs: Why medium matters. [PDF]

STAR Protoc
Gankema AAF, van Oosterom F, Kuijpers TW.   +2 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Seroprevalence and Temporal Trends of Syphilis Among Blood Donors at Dhiraj Blood Bank in Waghodia, Gujarat, India: A Retrospective Study. [PDF]

Cureus
Gosai D, Modi F, Parmar NJ, Chhaya K.
europepmc   +1 more source