Hormone replacement therapy is associated with improved verbal declarative memory in healthy relatively recent postmenopausal women. [PDF]
The efficacy of Hormone Replacement Therapy (HRT) for cognitive health in postmenopausal women has been systematically questioned during the last decade.
Sünram-Lea, Sandra I. +3 more
core +5 more sources
Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O. +5 more
core +6 more sources
Cell Therapy: Replacement [PDF]
Not long ago, the ability of the brain to restore function through regeneration of neural elements was thought to be nonexistent. It is now known that not only does some regenerative capacity exist, but implanted cells can integrate into the host brain, survive, and reverse neurological deficits.
Lawrence R, Wechsler +1 more
openaire +2 more sources
Thrombotic variables and risk of idiopathic venous thromboembolism in women aged 45-64 years - Relationships to hormone replacement therapy [PDF]
Hormone replacement therapy (HRT) has been shown to increase the relative risk of idiopathic venous thromboembolism (VTE) about threefold in several observational studies and one randomised controlled trial. Whether or not this relative risk is higher in
Rumley, A. +5 more
core +6 more sources
Dehydroepiandrosterone replacement therapy [PDF]
Dehydroepiandrosterone (DHEA) and its sulphated derivative DHEAS are the most abundant circulating steroids, and are derived from the zona reticularis of the adrenal cortex. The foetal adrenals synthesise signi®cant quantities of DHEA, but production of this steroid falls postnatally.
E M, Gurnell, V K, Chatterjee
openaire +2 more sources
A Distinct Urinary Biomarker Pattern Characteristic of Female Fabry Patients That Mirrors Response to Enzyme Replacement Therapy [PDF]
Female patients affected by Fabry disease, an X-linked lysosomal storage disorder, exhibit a wide spectrum of symptoms, which renders diagnosis, and treatment decisions challenging.
Breunig Frank +81 more
core +1 more source
Testosterone replacement therapy [PDF]
Abstract Background The aim of testosterone replacement therapy (TRT) is to improve symptoms and signs of testosterone deficiency including decreased libido, erectile dysfunction, depressed mood, anaemia, loss of muscle and bone mass, by increasing serum testosterone levels to physiologic range.
Barbonetti A. +2 more
openaire +2 more sources
Randomised controlled trial of an interactive multimedia decision aid on hormone replacement therapy in primary care [PDF]
Objective To determine whether a decision aid on hormone replacement therapy influences decision making and health outcomes.Design Randomised controlled trial.Setting 26 general practices in the United Kingdom.Participants 205 women considering hormone ...
Davis, H +5 more
core +1 more source
Comparison of siRNA-mediated silencing of glycosaminoglycan synthesis genes and enzyme replacement therapy for mucopolysaccharidosis in cell culture studies [PDF]
Cytotoxicity of laronidase (Aldurazyme®), employed in enzyme replacement therapy (ERT) for mucopolysaccharidosis type I (MPS I) and various siRNAs, tested previously in studies on substrate reduction therapy (SRT) for mucopolysaccharidoses, was ...
Banecka-Majkutewicz, Zyta +5 more
core +2 more sources
Plasmalogen Replacement Therapy [PDF]
Plasmalogens, a subclass of glycerophospholipids containing a vinyl-ether bond, are one of the major components of biological membranes. Changes in plasmalogen content and molecular species have been reported in a variety of pathological conditions ranging from inherited to metabolic and degenerative diseases.
José Carlos Bozelli, Richard M. Epand
openaire +3 more sources

