Results 41 to 50 of about 2,816,049 (194)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Лечение первичного гипотиреоза: нерешенные вопросы

Клиническая и экспериментальная тиреоидология, 2015
Primary hypothyroidism is one of the most common endocrine disorders. According to modern concepts, replacement monotherapy with levothyroxine (L-T4) is the treatment of choice in primary hypothyroidism.
Tatyana Borisovna Morgunova, Meruert Shayzindinovna Madiyarova, Valentin Viktorovich Fadeyev   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Circadian and individual variability of TSH level in patients received replacement therapy for primary hypothyroidism

Клиническая и экспериментальная тиреоидология, 2010
Objective: to investigate circadian and individual variability of TSH level in patients taking LT4-replacement therapy for primary hypothyroidism. Methods.

doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effectiveness of additional topical antibiotics for recurrent or refractory exit-site infection: a case series

Renal Replacement Therapy
Background Japanese peritoneal dialysis (PD) guidelines do not suggest applying mupirocin/gentamicin ointment to the exit sites of PD patients to prevent exit-site infection (ESI).
Nao Asai, Yasuhiro Suzuki, Akimasa Asai, Hiroshi Kinashi, Keisuke Kamiya, Junichiro Hagita, Naoya Matsuoka, Suzuka Kawamura, Sosuke Fukui, Hangsoo Kim, Makoto Yamaguchi, Takayuki Katsuno, Masashi Mizuno, Takuji Ishimoto, Yasuhiko Ito   +14 more
doaj   +1 more source

Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection

Immunobiology
Background: Malaria is an important and serious parasite-induced disease associated with severe anemia and multiple organ failure (MOF) that can be lethal in humans.
Tomoaki Kamiya, Yuki Miyasaka, Hangsoo Kim, Sosuke Fukui, Masatoshi Inoue, Masatoshi Ishigami, Yasuhiro Suzuki, Shoichi Maruyama, Tamio Ohno, Timothy R. Hughes, B. Paul Morgan, Masashi Mizuno   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Recent Advances in the Treatment of Hemophilia: A Review

Biologics: Targets & Therapy, 2021
Emanuela Marchesini,1 Massimo Morfini,2 Leonard Valentino3,4 1Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Perugia, Italy; 2Italian Association of Haemophilia Centres (AICE), Naples, Italy; 3National Hemophilia ...
Marchesini E, Morfini M, Valentino L
doaj  

SECONDARY HYPOTHYROIDISM: CURRENT APPROACHES TO DIAGNOSIS AND TREATMENT

Медицинский совет, 2017
Secondary hypothyroidism is a very rare cause of hypothyroidism in adults. Clinical manifestations of secondary as well as primary hypothyroidism are nonspecific; in addition, thyroid hormone deficiency often clinically simulates other tropic hormone ...
T. A. Gavrilova, T. B. Morgunova, V. V. Fadeev   +2 more
doaj   +1 more source