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Pembrolizumab-associated primary hypothyroidism followed by central hypothyroidism: a case report [PDF]

Frontiers in Oncology
IntroductionPD-1 inhibitors are widely used anticancer drugs and frequently trigger immune-related adverse events, with thyroid dysfunction as the most prevalent. Suspected isolated central hypothyroidism emerging during PD-1 inhibitor therapy has rarely
Jiawei Sun, Chunnuo Wang, Zhanzhan Sun, Wei Li   +3 more
doaj   +2 more sources

Thyroid testing in primary hypothyroidism [PDF]

African Journal of Primary Health Care & Family Medicine
Thyroid hormones regulate essential metabolic processes and development. The hypothalamic–pituitary–thyroid axis regulates hormone production, with thyroid-stimulating hormone (TSH) levels being a key indicator of thyroid function in primary ...
Anshula Ambasta, Guillaume Grenet, Jessica Otte, Wade Thompson, Kenneth Bassett, Thomas Perry   +5 more
doaj   +2 more sources

Treatment for primary hypothyroidism: current approaches and future possibilities

Drug Design, Development and Therapy, 2011
Ali J Chakera1, Simon HS Pearce2, Bijay Vaidya11Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter, 2Endocrine Unit, Royal Victoria Infirmary and Newcastle University, Newcastle upon Tyne, UKAbstract ...
Chakera AJ, Pearce SHS, Vaidya B
doaj   +2 more sources

Evaluating Features of Congenital Primary Hypothyroidism and Its Outcomes in Mongolia

Central Asian Journal of Medical Sciences, 2021
Objectives: Our goal was to assess the outcomes of congenital primary hypothyroidism and evaluate forms of dysgenesis forms among children diagnosed with congenital primary hypothyroidism Methods: A cross-sectional study recruited all children diagnosed ...
Altantuya Tsevgee, Tsolmon Munkhchuluun, Naranchimeg Khurelbaatar, Gerelmaa Zagd, Erdenetuya Ganbaatar   +4 more
doaj   +1 more source

Diabetes among Patients with Overt Primary Hypothyroidism Visiting the Outpatient Department of General Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2023
Introduction: Thyroid diseases are one of the commonest endocrine disorders and hypothyroidism is the commonest among them. There are many publications about hypothyroidism prevalence in diabetes, however, reports of diabetes in hypothyroidism are ...
Sadikshya Poudel, Mubashir Angolkar, Arif Maldar   +2 more
doaj   +1 more source

Hypothyroidism: current state of the problem

Медицинский совет, 2020
The article presents the issues of epidemiology, classification, and clinic of hypothyroidism. The frequency of hypothyroidism increases significantly with age.
E. V. Biryukova, D. V. Kileynikov, I. V. Solovyeva   +2 more
doaj   +1 more source

The Correlation between Serum Inositol 1,4,5 Triphosphate Level and Primary Hypothyroidism

مجله كليه طب الكندي, 2022
Background: Most primary hypothyroidism patients also experience inefficiency and irregularity. It is possible to understand the significance of myo-inositol in treating the thyroid gland by relating it to the synthesis of thyroid hormones.
Akram Sabah Matshar, Maysaa Jalal Majeed, Mohamed Sadoon Mohson   +2 more
doaj   +1 more source

Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.

PLoS ONE, 2021
IntroductionThe presence of rheumatism is well recognized in primary hypothyroidism. Dehydroepiandrstenedione sulphate (DHEAS) is associated with rheumatological diseases like rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
Ravindra Shukla, Mayank Ganeshani, Monica Agarwal, Rakesh Jangir, Gaurav Kandel, Shrimanjunath Sankanagoudar, Shival Srivastava   +6 more
doaj   +1 more source

Dose-volume predictors of post-radiation primary hypothyroidism in head and neck cancer: A systematic review

Clinical and Translational Radiation Oncology, 2022
Background and Purpose: This systematic review aims to identify radiation dose-volume predictors of primary hypothyroidism after radiotherapy in patients with head and neck cancer (HNC).
James C.H. Chow, Ka-Man Cheung, Gavin T.C. Cheung, Anthony H.P. Tam, Jeffrey C.F. Lui, Francis K.H. Lee, Kwok-Hung Au, Wai-Tong Ng, Anne W.M. Lee, Harry H.Y. Yiu   +9 more
doaj   +1 more source

Lipid Profile Abnormalities in Newly Diagnosed Primary Hypothyroidism in a Tertiary Care Centre of Western Nepal: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2021
Introduction: Thyroid hormones have a major influence on synthesis, mobilization and metabolism of lipids. Hypothyroidism accounts for a notable cause of secondary dyslipidemia. This can increase the risk for cardiovascular morbidity and mortality.
Prabin Khatri, Aryan Neupane, Ashish Banjade, Suman Sapkota, Smile Kharel, Ashmita Chhetri, Dipesh Sharma, Saphal Nath Subedi, Pradip Chhetri   +8 more
doaj   +1 more source