Results 11 to 20 of about 4,672,466 (296)

Calcitonin Deficiency in Primary Hypothyroidism*

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1986
The relative lack of sensitivity and specificity of current assays for plasma calcitonin (CT) have made it difficult to study possible CT deficiency conditions. Using a new extraction method that considerably improves the sensitivity of the assay for CT monomer, CT levels were measured before and after a short calcium (Ca) stimulation test (2 mg Ca/kg ...
Body, Jean-Jacques   +4 more
openaire   +4 more sources

Levothyroxine improves Paraoxonase (PON-1) serum levels in patients with primary hypothyroidism: Case–control study

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2018
Primary hypothyroidism is associated with oxidative stress and insufficient antioxidant capacity. This study was conducted to evaluate the effects of levothyroxine replacement therapy on paraoxonase 1 (PON-1) serum levels in a patients with primary ...
Marwa S Al-Naimi   +4 more
doaj   +2 more sources

Pituitary Hyperplasia in Severe Primary Hypothyroidism: A Case Report and Review of the Literature

open access: yesCase Reports in Endocrinology, 2019
Pituitary hyperplasia is commonly present but remains largely undiagnosed in primary hypothyroidism. It is easily reversible with thyroid replacement therapy.
Prateek Shukla   +2 more
doaj   +2 more sources

Ocular changes in primary hypothyroidism [PDF]

open access: yesBMC Research Notes, 2009
Background To determine the ocular changes related to hypothyrodism in newly diagnosed patients without orbitopathy. Findings Thirty-three patients diagnosed to have primary overt hypothyroidism were enrolled in the study.
Pekel Hamiyet   +4 more
doaj   +4 more sources

Newly diagnosed primary hypothyroidism applicant with massive pericardial effusion and acute renal failure

open access: yesEndocrine Regulations, 2016
Objective. While non-symptomatic pericardial effusion is seen in primary hypothyroidism, massive pericardial effusion is a very rare finding. In the literature, newly diagnosed primary hypothyroidism cases presenting with massive pericardial effusion or ...
Ates I, Kaplan M, Yilmaz N
doaj   +2 more sources

Inherited Primary Hypothyroidism in Mice

open access: yesScience, 1981
A new autosomal recessive mutation that causes hypothyroidism has been identified in mice. The gene, herein named hypothyroid ( hyt ), has been mapped on chromosome 12 approximately 30 units from the centromere. The mutants are characterized by retarded growth, infertility, mild anemia, elevated serum cholesterol ...
Beamer, W G   +3 more
core   +4 more sources

Ascites, pleural, and pericardial effusion in primary hypothyroidism: a rare case report

open access: yes, 2023
Hypothyroidism is caused by a deficiency of thyroid hormones and is a common endocrine disorder worldwide. It can affect nearly every organ, resulting in multiple clinical manifestations. Ascites, pleural effusion, and pericardial effusion, although less
Mogildea, Mihail   +4 more
core   +1 more source

Diagnosis and Treatment of Primary Hypothyroidism in Primary Care

open access: yes, 2022
Decreased thyroid function occurs among 0,2–1% of men and 1,4–5% of women in the general population, and among people over 60 years among 2,5% of men and 6% of women.
Protsiuk Olha
core   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Primary hypothyroidism and quality of life

open access: yesNature Reviews Endocrinology, 2022
In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic L form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of hypothyroidism. The biochemical definition of subclinical hypothyroidism is a matter of debate.
Laszlo Hegedüs   +5 more
openaire   +3 more sources

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