Results 51 to 60 of about 3,519,757 (299)

Circadian and individual variability of TSH level in patients received replacement therapy for primary hypothyroidism

Клиническая и экспериментальная тиреоидология, 2010
Objective: to investigate circadian and individual variability of TSH level in patients taking LT4-replacement therapy for primary hypothyroidism. Methods.

doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Effectiveness of additional topical antibiotics for recurrent or refractory exit-site infection: a case series

Renal Replacement Therapy
Background Japanese peritoneal dialysis (PD) guidelines do not suggest applying mupirocin/gentamicin ointment to the exit sites of PD patients to prevent exit-site infection (ESI).
Nao Asai, Yasuhiro Suzuki, Akimasa Asai, Hiroshi Kinashi, Keisuke Kamiya, Junichiro Hagita, Naoya Matsuoka, Suzuka Kawamura, Sosuke Fukui, Hangsoo Kim, Makoto Yamaguchi, Takayuki Katsuno, Masashi Mizuno, Takuji Ishimoto, Yasuhiko Ito   +14 more
doaj   +1 more source

Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection

Immunobiology
Background: Malaria is an important and serious parasite-induced disease associated with severe anemia and multiple organ failure (MOF) that can be lethal in humans.
Tomoaki Kamiya, Yuki Miyasaka, Hangsoo Kim, Sosuke Fukui, Masatoshi Inoue, Masatoshi Ishigami, Yasuhiro Suzuki, Shoichi Maruyama, Tamio Ohno, Timothy R. Hughes, B. Paul Morgan, Masashi Mizuno   +11 more
doaj   +1 more source

Recent Advances in the Treatment of Hemophilia: A Review

Biologics: Targets & Therapy, 2021
Emanuela Marchesini,1 Massimo Morfini,2 Leonard Valentino3,4 1Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Perugia, Italy; 2Italian Association of Haemophilia Centres (AICE), Naples, Italy; 3National Hemophilia ...
Marchesini E, Morfini M, Valentino L
doaj  

SECONDARY HYPOTHYROIDISM: CURRENT APPROACHES TO DIAGNOSIS AND TREATMENT

Медицинский совет, 2017
Secondary hypothyroidism is a very rare cause of hypothyroidism in adults. Clinical manifestations of secondary as well as primary hypothyroidism are nonspecific; in addition, thyroid hormone deficiency often clinically simulates other tropic hormone ...
T. A. Gavrilova, T. B. Morgunova, V. V. Fadeev   +2 more
doaj   +1 more source

Thyroxine replacement therapy

Clinical Endocrinology, 1991
There is much debate about what is the correct dose of thyroxine replacement therapy and whether suppression of the serum TSH concentration, when measured by an assay with a lower limit of detection of 0.1 mU/l or less, is a risk factor for osteoporosis.
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Safety of hormone replacement therapy after mastectomy [PDF]

, 2002
After mastectomy, chemotherapy and radiotherapy for high-grade ductal carcinoma with nodal involvement and lymphatic infiltration, a 48-year-old woman had premature menopause, with symptoms of loss of libido.
Glasziou, Paul P, Sanders, Sharon L, Mar, Christopher B Del, Spinks, Anneliese Barclay, Hilton, Deborah J   +4 more
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