Results 31 to 40 of about 33,125 (245)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Replicas. Architecture as Copy or Invention
RA. Revista de Arquitectura, 2022 Carolina-B. García-Estévez
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Victoria, Mexico, Earthquake of June 9, 1980
Geofísica Internacional, 1997 El sismo de Victoria de junio 9 de 1980 (ML = 6.1) ocurrió en el Valle de Mexicali cerca de la traza de la falla de Cerro Prieto con un mecanismo focal de fallamiento de rumbo con movimiento lateral derecho en un plano vertical.
V. Wong, J. Frez, F. Suarez
doaj +1 more source
La renta básica. Críticas y réplicas
Revista Internacional de Pensamiento Político, 2021 La renta básica es un tema recurrente en la agenda de los políticos, en la opinión pública y en la doctrina de los expertos. Curiosamente ha sido justificada desde diversas concepciones políticas: el socialismo, el republicanismo e incluso el liberalismo.
Ramón Luis Soriano Díaz
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Geofísica Internacional, 1978 Entre el 20 de enero y el 18 de abril de 1979, el lnstituto de Geofísica, UNAM y el Laboratorio Sismológico, CALTECH operaron conjuntamente una red local de estaciones sismológicas portátiles al sur del Estado de Oaxaca, con el objeto de observar las ...
F. Nuñez-Cornu +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source