Results 51 to 60 of about 56,188 (281)
Concrete and non-concrete: exploring the contemporary authenticity of historic replicas through an ethnographic study of the St John's Cross replica, Iona [PDF]
, 2019 What do we actually know about how replicas of historical objects and monuments 'work' in heritage contexts, in particular their cultural significance and intangible values?
Foster, Sally M, Jones, Siân
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Teens, manga and replica shabtis
Archaeology International, 2022 The Teens, Manga and Digitally Produced Replicas Project, which brings together archaeologically charged replicas, members of the ‘youth generation community’ and manga cartoons, forms part of PhD research at the Institute of Archaeology.
doaj +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Complementary Replicas of Ultra-Rapidly Frozen Specimens [PDF]
, 1985 Complementary freeze-fracture replicas have been prepared of ultra-rapidly cooled specimens in the absence of chemical pretreatments. The grid-sized replicas were stabilized by open mesh gold grids during the cleaning process and, after cleaning, were ...
Fetter, R. D. +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A 3D modelling approach to measuring structural characteristics of bird nest interiors
Methods in Ecology and EvolutionNests are considered extended phenotypes of animals with potentially serious fitness consequences for the survival of offspring. Therefore, nest characteristics may contain valuable information about the underlying ecological and evolutionary mechanisms ...
Jing‐Chia Guo +2 more
doaj +1 more source