Results 71 to 80 of about 56,188 (281)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Intentional patterns in replicas of interlocutors
Intentional characteristics of dialogue and their modification in the process of interaction are studied on the basis of authentic conversations of the students.
V.A. Afinogenova, N.D. Pavlova
doaj +1 more source
Avoiding False Positive Conclusions in Molecular Simulation:The Importance of Replicas [PDF]
Molecular simulations are a computational technique used to investigate the dynamics of proteins and other molecules. The free energy landscape of these simulations is often rugged, and minor differences in the initial velocities, floating-point ...
Bernhard Knapp +12 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Traprain Treasure silver replicas
Every so often an archaeological discovery comes along that grips the imagination of the public. This fascination with the past has driven a production line of replicas, making ‘ancient’ artefacts available for those that wish to own a piece of history ...
McGill, Lyndsay
core
Creating and sharing 3D digital replicas of archaeological sites online has become increasingly common. They are being integrated in excavation workflows, used to foster public engagement with the site, and provide communication and outreach of research,
Sechaba Maape +11 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FReDi : Flexible Replicas Displacer
International audienceWe present in this article a flexible management system for dynamic placement of content replicas. It is able to satisfy users' constraints and preferences, while limiting the load of servers and proxy-caches.
Gossa, Julien +2 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
In wireless sensor networks, replica node attacks are very dangerous because the attacker can compromise a single node and generate as many replicas of the compromised node as he wants, and then exploit these replicas to disrupt the normal operations of ...
Jun-Won Ho
doaj +1 more source

