Results 61 to 70 of about 57,217 (289)

Comparative evaluation of the shaping performance of three NiTi rotary systems in distolingual canals of 3D-printed three-rooted mandibular first molars

open access: yesFrontiers in Dental Medicine
IntroductionThis ex vivo study compared the shaping ability of three nickel-titanium (NiTi) rotary systems in distolingual (DL) canals using 3D-printed three-rooted mandibular first molar (3RM1) replicas.Materials and methodsTwo extracted 3RM1s with DL ...
Bingbing Bai   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

FReDi : Flexible Replicas Displacer

open access: yes, 2006
International audienceWe present in this article a flexible management system for dynamic placement of content replicas. It is able to satisfy users' constraints and preferences, while limiting the load of servers and proxy-caches.
Gossa, Julien   +5 more
core   +1 more source

Complementary Replicas of Ultra-Rapidly Frozen Specimens [PDF]

open access: yes, 1985
Complementary freeze-fracture replicas have been prepared of ultra-rapidly cooled specimens in the absence of chemical pretreatments. The grid-sized replicas were stabilized by open mesh gold grids during the cleaning process and, after cleaning, were ...
Fetter, R. D.   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

High resolution replicas [PDF]

open access: yes, 1988
Disclosed are improved methods for preparing high resolution replicas for electron microscopic analysis. Replicas are prepared having a resolution capability less than ten angstroms, with structures of even less than five angstroms being readily ...
Mizuta, Shun, Brown, R. Malcolm, Jr.
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Detecting near replicas on the Web by content and hyperlink analysis

open access: yes, 2003
The presence of replicas or near-replicas of documents is very common on the Web. Whilst replication can improve information accessibility for the users, the presence of near-replicas can hinder the effectiveness of search engines. We propose a method to
Marco Maggini   +14 more
core   +1 more source

A 3D modelling approach to measuring structural characteristics of bird nest interiors

open access: yesMethods in Ecology and Evolution
Nests are considered extended phenotypes of animals with potentially serious fitness consequences for the survival of offspring. Therefore, nest characteristics may contain valuable information about the underlying ecological and evolutionary mechanisms ...
Jing‐Chia Guo   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy